Skip to main content

Main menu

  • Home
  • About
    • About CBM
    • Editorial Board
    • Announcement
  • Articles
    • Ahead of print
    • Current Issue
    • Archive
    • Collections
    • Cover Story
  • For Authors
    • Instructions for Authors
    • Resources
    • Submit a Manuscript
  • For Reviewers
    • Become a Reviewer
    • Instructions for Reviewers
    • Resources
    • Outstanding Reviewer
  • Subscription
  • Alerts
    • Email Alerts
    • RSS Feeds
    • Table of Contents
  • Contact us
  • Other Publications
    • cbm

User menu

  • My alerts

Search

  • Advanced search
Cancer Biology & Medicine
  • Other Publications
    • cbm
  • My alerts
Cancer Biology & Medicine

Advanced Search

 

  • Home
  • About
    • About CBM
    • Editorial Board
    • Announcement
  • Articles
    • Ahead of print
    • Current Issue
    • Archive
    • Collections
    • Cover Story
  • For Authors
    • Instructions for Authors
    • Resources
    • Submit a Manuscript
  • For Reviewers
    • Become a Reviewer
    • Instructions for Reviewers
    • Resources
    • Outstanding Reviewer
  • Subscription
  • Alerts
    • Email Alerts
    • RSS Feeds
    • Table of Contents
  • Contact us
  • Follow cbm on Twitter
  • Visit cbm on Facebook
Research ArticleResearch Article

Detection of Homozygous Deletions and Mutations in the CDKN2A Gene in Hydatidiform Moles

Jing Wang, Shuying Wu, Ying Gu, Yan Zhu and Xiaowei Zhang
Chinese Journal of Clinical Oncology April 2008, 5 (2) 99-102; DOI: https://doi.org/10.1007/s11805-008-0099-y
Jing Wang
1Department of Gynecology and Obstetrics, Peking University Third Hospital, Beijing 100083, China.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Shuying Wu
1Department of Gynecology and Obstetrics, Peking University Third Hospital, Beijing 100083, China.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ying Gu
2Department of Genetics, Beijing Haidian Maternal and Child Health Hospital, Beijing 100080, China.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yan Zhu
3Department of Gynecology and Obstetrics, Affiliated First Hospital of Liaoning Medical College, Jinzhou 121001, Liaoning province, China.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Xiaowei Zhang
1Department of Gynecology and Obstetrics, Peking University Third Hospital, Beijing 100083, China.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: zhangxw{at}bjmu.edu.cn
  • Article
  • Figures & Data
  • Info & Metrics
  • References
  • PDF
Loading

References

  1. ↵
    1. Tian G,
    2. Ma J,
    3. Wang J.
    Research of homozygous deletion of gene p14ARF and expression of its product in thyroid tumors. Chin J Cancer Prev Treat 2005; 12: 1292-1294 (Chinese).
    OpenUrl
  2. ↵
    1. Stott FJ,
    2. Bates S,
    3. James MC, et al.
    The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2. EMBO J 1998; 17: 5001-5014.
    OpenUrlAbstract/FREE Full Text
  3. ↵
    1. Chen L,
    2. Li Y,
    3. Gao L.
    The anylasis of P16 gene deletion and mutation in esophageal squamous cell carcinoma. Chin J Clin Oncol 2004; 31: 1381-1384 (Chinese).
    OpenUrl
    1. Zhang L,
    2. Wang S,
    3. Wang X, et al.
    Quantitative and qualitative assay of p16 in esophageal carcinoma and precancerous lesion. Chin J of Clin Oncol 2006; 33: 427-430 (Chinese).
    OpenUrl
  4. ↵
    1. Gao L,
    2. Hu Y,
    3. Li J, et al.
    The relationship between INK4a/ARF genes methylation and proteins coexpression in non-small cell lung cancer. Chin J Clin Oncol 2006, 33: 130-133 (Chinese).
    OpenUrl
  5. ↵
    1. Scacchi R,
    2. Gambina G,
    3. Moretto G, et al.
    A mutation screening by DHPLC of PSEN1 and APP genes reveals no significant variation associated with the sporadic late-onset form of Alzheimer’s disease. Neurosci Lett 2007; 418: 282-285.
    OpenUrlPubMed
  6. ↵
    1. Kleibl Z,
    2. Havranek O,
    3. Prokopcova J, et al.
    Rapid detection of CAA/CAG repeat polymorphism in the AIB1 gene using DHPLC. Biochem Biophys Methods 2007; 70: 511–513.
    OpenUrlPubMed
  7. ↵
    1. Underhill PA,
    2. Jin L,
    3. Lin AA, et al.
    Detection of numerous Y chromosome biallelic polymorphisms by denaturing high-performance liquid chromatography. Genome Res 1997; 7: 996–1005.
    OpenUrlAbstract/FREE Full Text
  8. ↵
    1. Zhang L,
    2. Xu G,
    3. Nicholas CP, et al.
    Application of denaturing high performance liquid chromatography to mutation detection of the c-kit gene in mastocytosis. Cross J Exp Hematol 2006; 14: 981-984 (Chinese).
    OpenUrl
  9. ↵
    1. Wang Z,
    2. Dai S,
    3. Luo B.
    The value of p16 and p15 genes in predicting canceration of hydatidiform mole. Med J Qilu 2005; 20: 117-121 (Chinese).
    OpenUrl
  10. ↵
    1. Xue WC,
    2. Chan KYK,
    3. Feng HC, et al.
    Promoter hypermethylation of multiple genes in hydatidiform mole and choriocarcinoma. J Mol Diagn 2004; 6: 326-332.
    OpenUrlCrossRefPubMedWeb of Science
  11. ↵
    1. Pineau P,
    2. Marchio A,
    3. Cordina E, et al.
    Homozygous deletions scanning in tumor cell lines detects previously unsuspected loci. Int J Cancer 2003; 106: 216-223.
    OpenUrlCrossRefPubMedWeb of Science
  12. ↵
    1. Grafstrom E,
    2. Egyhazi S,
    3. Ringborg U, et al.
    Biallelic deletions in INK4 in cutaneous melanoma are common and associated with decreased survival. Clin Cancer Res 2005; 1: 2991-2997.
    OpenUrl
  13. ↵
    1. Chang LL,
    2. Yeh WT,
    3. Yang SY, et al.
    Genetic alterations of p16INK4a and p14ARF genes in human bladder cancer. J Urol 2003; 170: 595-600.
    OpenUrlCrossRefPubMed
PreviousNext
Back to top

In this issue

Cancer Biology and Medicine: 5 (2)
Chinese Journal of Clinical Oncology
Vol. 5, Issue 2
April 2008
  • Table of Contents
  • Index by author
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on Cancer Biology & Medicine.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Detection of Homozygous Deletions and Mutations in the CDKN2A Gene in Hydatidiform Moles
(Your Name) has sent you a message from Cancer Biology & Medicine
(Your Name) thought you would like to see the Cancer Biology & Medicine web site.
Citation Tools
Detection of Homozygous Deletions and Mutations in the CDKN2A Gene in Hydatidiform Moles
Jing Wang, Shuying Wu, Ying Gu, Yan Zhu, Xiaowei Zhang
Chinese Journal of Clinical Oncology Apr 2008, 5 (2) 99-102; DOI: 10.1007/s11805-008-0099-y

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Detection of Homozygous Deletions and Mutations in the CDKN2A Gene in Hydatidiform Moles
Jing Wang, Shuying Wu, Ying Gu, Yan Zhu, Xiaowei Zhang
Chinese Journal of Clinical Oncology Apr 2008, 5 (2) 99-102; DOI: 10.1007/s11805-008-0099-y
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • References
  • PDF

Related Articles

  • No related articles found.
  • Google Scholar

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • Efficacy and Immune Mechanisms of Cetuximab for the Treatment of Metastatic Colorectal Cancer
  • Pemetrexed Monotherapy and Pemetrexed Plus Platinum Combination Therapy as Non-First-Line Treatments for Advanced Non-Small Cell Lung Cancer
  • Multi-Targeted Therapies in Non-Small Cell Lung Cancer
Show more Research Article

Similar Articles

Keywords

  • hydatidiform mole
  • CDKN2A gene
  • homozygous deletion
  • mutation

Navigate

  • Home
  • Current Issue

More Information

  • About CBM
  • About CACA
  • About TMUCIH
  • Editorial Board
  • Subscription

For Authors

  • Instructions for authors
  • Journal Policies
  • Submit a Manuscript

Journal Services

  • Email Alerts
  • Facebook
  • RSS Feeds
  • Twitter

 

© 2026 Cancer Biology & Medicine

Powered by HighWire