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Pan-KRAS inhibition: unlocking broad-spectrum targeted therapy for KRAS-mutant cancers
Juanjuan Feng, Xuanzheng Xiao, Zhengke Lian, Ao Zhang and Xiufeng Pang

Cancer Biology & Medicine February 2026, 20250612; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0612

Open Access
Gut microecology empowers cancer immunotherapy: commensal microbiota-mediated mechanisms and translational prospects of PD-1/PD-L1 therapy
Sifan Li, Chang Che, Yelu Zhou, Daiming Fan, Xue Bai, Yuanyuan Lu and Xiaodi Zhao

Cancer Biology & Medicine January 2026, 20250347; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0347
Open Access
Rethinking anti-cancer drug discovery: the evolution from polypharmacy to unified drug units
Jun He and Xinbing Sui

Cancer Biology & Medicine January 2026, 20250641; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0641

Open Access
SPRED2 suppresses the stemness of hepatocellular carcinoma through the p53/miR-506-3p/KLF4 pathway
Tong Gao, Sachio Ito, Aye Moh-Moh-Aung, Tianyi Wang, Masayoshi Fujisawa, Toshiaki Ohara, Teizo Yoshimura and Akihiro Matsukawa

Cancer Biology & Medicine January 2026, 20250247; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0247
Open Access
Innovative cross-intervention: copper ions and metabolic pathways in cancer therapy
Lili Niu, Wei Su, Lixia Ju, Jun Xiang, Zhou Yang and Bing Yao

Cancer Biology & Medicine January 2026, 20250198; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0198

Open Access
Migration and invasion inhibitory protein inhibits M2 macrophage polarization to suppress colorectal cancer progression through the STING–NFκB2–IL10 axis
Shuai Chen, Chenglu Lu, Jiaxin Li, Xilin Shen and Yan Sun

Cancer Biology & Medicine January 2026, 20250282; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0282
Open Access
Temporal radiomics for non-invasive preoperative prediction of pathologic complete response to neoadjuvant chemoimmunotherapy in non-small cell lung cancer
Sunyi Zheng, Shuo Wang, Ziwei Feng, Jing Liang, Jiaxin Liu, Xiaomeng Yang, Zhanshuo Zhang, Yuechen Cui, Jiping Xie, Shuxuan Fan, Jing Wang, Guoqing Liao, Haiyu Zhou, Zhaoxiang Ye, Jianyu Xiao, Lei Shi, Xiaonan Cui and Dongsheng Yue

Cancer Biology & Medicine January 2026, 20250327; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0327

Open Access
Multi-cancer early detection: from promise to practice and the next frontier
Yongjie Xu and Wanqing Chen

Cancer Biology & Medicine December 2025, 20250664; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0664

Open Access
Impact of pre-neoadjuvant radioactive iodine seed marking on pathologic complete response and survival in early-stage breast cancer patients
Yihao Geng, Qi Zhang, Zhao Bi, Zhiqiang Shi, Qiuchen Zhao, Xiaowei Qi, Rongrong Zhao, Yongsheng Wang and Pengfei Qiu

Cancer Biology & Medicine December 2025, 20250578; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0578
Open Access
Tumor microenvironment-responsive polymeric nanoparticles for enhanced immunotherapy
Yongxin Zhang, Shaobing Zhou and Jingya Zhao

Cancer Biology & Medicine December 2025, 20250517; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0517

Open Access
Introduction and impact of the young breast cancer in China consensus
Xin Yang, Chao Dong and Qiang Liu

Cancer Biology & Medicine December 2025, 20250523; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0523

Open Access
Cancer stem cells in hepatocellular carcinoma: platforms, updates, challenges and future perspectives
Jingyi Lu, Diana Chui-Yee O, Yu-Man Tsui and Irene Oi-Lin Ng

Cancer Biology & Medicine December 2025, 20250622; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0622

Open Access
Enhancing cancer immunotherapy through polymer-based antibody conjugation technologies
Hongyu Chu, Jun Chen, Sheyu Ye, Xuedong Fang, Na Shen and Zhaohui Tang

Cancer Biology & Medicine November 2025, 20250512; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0512

Open Access
Global disparities in childhood neuroblastoma: trends, burden, and inequities from 1990 to 2021
Rui Zhang, Yang Bi, Feifei Bao, Feixia Pan, Weize Xu, Qiang Shu, Zhigang Liu and Daqing Ma

Cancer Biology & Medicine July 2025, 20250163; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0163
Open Access
The arginine metabolism battlefield: how metabolite exchange in the tumor microenvironment shapes an immunosuppressive ecosystem
Yinghua Zhu, Hongde Li, Hongbo Hu, Hai Hu and Man-Li Luo

Cancer Biology & Medicine July 2025, 20250202; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0202

Open Access
Organoid models in oncology: advancing precision cancer therapy and vaccine development
Yuxuan Xiao, Yutao Li, Xilin Jing, Lin Weng, Xu Liu, Qingyun Liu and Kezhong Chen

Cancer Biology & Medicine July 2025, 20250127; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0127

Open Access
Comprehensive strategies for management of postoperative hyper-progression recurrence (HPR) of hepatocellular carcinoma: a 12-year large sample multi-center study
Lunan Qi, Jingxuan Xu, Yuanyuan Chen, Zhan Lu, Min Zhou, Yingwu Huang, Yongchi Ling, Hai Huang, Yuchong Peng, Tao Peng, Bangde Xiang and Liang Ma

Cancer Biology & Medicine July 2025, 20240514; DOI: https://doi.org/10.20892/j.issn.2095-3941.2024.0514

Open Access
Novel diagnostic and therapeutic strategies based on PANoptosis for hepatocellular carcinoma
Jie Xiang, Yukai Li, Shengmin Mei, Zhiyan Ou, Li Wang, Yang Ke and Zhiwei Li

Cancer Biology & Medicine July 2025, 20250150; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0150

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