Research ArticleResearch Article
Identification of the Tumor Factor of Abnormal Cancer Methylation Enzymes as the Catalytic Subunit of Telomerase
Ming C. LIAU, Pei-zhuang ZHU and George C. Y. CHIOU
Clinical Oncology and Cancer Research April 2010, 7 (2) 86-96; DOI: https://doi.org/10.1007/s11805-010-0501-4
Ming C. LIAU
Institute of Ocular Pharmacology, College of Medicine, Texas A&M Health Science Center, College Station, TX 77845, USA.
Pei-zhuang ZHU
Institute of Ocular Pharmacology, College of Medicine, Texas A&M Health Science Center, College Station, TX 77845, USA.
George C. Y. CHIOU
Institute of Ocular Pharmacology, College of Medicine, Texas A&M Health Science Center, College Station, TX 77845, USA.
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In this issue
Identification of the Tumor Factor of Abnormal Cancer Methylation Enzymes as the Catalytic Subunit of Telomerase
Ming C. LIAU, Pei-zhuang ZHU, George C. Y. CHIOU
Clinical Oncology and Cancer Research Apr 2010, 7 (2) 86-96; DOI: 10.1007/s11805-010-0501-4
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Keywords
- telomerase
- tumor factor of MATLT
- methylation enzymes
- differentiation
- AdoHcy: S-adenosylhomocysteine
- Ado-Met: S-adenosylmethionine
- Hsp: heat shock protein
- MAT: methionine adenosyltransferase
- MATL: the low Km isozyme of MAT
- MATLT: the tumor factor associated low Km isozyme of MAT
- Mr: molecular weight
- MT: methyltransferase
- PMSF: phenylmethylsulfonyl fluoride
- PP-0.39: pigment peptide with a Kav value of 0.39 on the Bio-Gel P2 column
- SAHH: S-adenosylhomocysteine hydrolase
- TERT: telomerase reverse transcriptase