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Review ArticleReview

Emerging data supporting stromal cell therapeutic potential in cancer: reprogramming stromal cells of the tumor microenvironment for anti-cancer effects

Armel Hervé Nwabo Kamdje, Paul Faustin Seke Etet, Richard Tagne Simo, Lorella Vecchio, Kiven Erique Lukong and Mauro Krampera
Cancer Biology & Medicine November 2020, 17 (4) 828-841; DOI: https://doi.org/10.20892/j.issn.2095-3941.2020.0133
Armel Hervé Nwabo Kamdje
1Department of Biomedical Sciences, University of Ngaoundere, Faculty of Science, Ngaoundere 454, Cameroon
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Paul Faustin Seke Etet
2Department of Physiological Sciences and Biochemistry, University of Ngaoundéré, Garoua 454, Cameroon
3Center for Sustainable Health and Development, Garoua 454, Cameroon
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Richard Tagne Simo
1Department of Biomedical Sciences, University of Ngaoundere, Faculty of Science, Ngaoundere 454, Cameroon
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Lorella Vecchio
3Center for Sustainable Health and Development, Garoua 454, Cameroon
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Kiven Erique Lukong
4Department of Biochemistry, Microbiology & Immunology, University of Saskatchewan, College of Medicine, Saskatoon SK S7N 5E5, Canada
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Mauro Krampera
5Department of Medicine, University of Verona, Section of Hematology, Stem Cell Research Laboratory, Verona 37134, Italy
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Article Information

vol. 17 no. 4 828-841
DOI 
https://doi.org/10.20892/j.issn.2095-3941.2020.0133

Published By 
Cancer Biology & Medicine
History 
  • Received March 24, 2020
  • Accepted August 20, 2020
  • Published online November 15, 2020.

Copyright & Usage 
Copyright: © 2020, Cancer Biology & Medicine https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY) 4.0, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

Author Information

  1. Armel Hervé Nwabo Kamdje1⇑,
  2. Paul Faustin Seke Etet2,3,
  3. Richard Tagne Simo1,
  4. Lorella Vecchio3,
  5. Kiven Erique Lukong4 and
  6. Mauro Krampera5
  1. 1Department of Biomedical Sciences, University of Ngaoundere, Faculty of Science, Ngaoundere 454, Cameroon
  2. 2Department of Physiological Sciences and Biochemistry, University of Ngaoundéré, Garoua 454, Cameroon
  3. 3Center for Sustainable Health and Development, Garoua 454, Cameroon
  4. 4Department of Biochemistry, Microbiology & Immunology, University of Saskatchewan, College of Medicine, Saskatoon SK S7N 5E5, Canada
  5. 5Department of Medicine, University of Verona, Section of Hematology, Stem Cell Research Laboratory, Verona 37134, Italy
  1. Correspondence to: Armel Hervé Nwabo Kamdje, E-mail: armel.nwabo{at}gmail.com
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Cancer Biology and Medicine: 17 (4)
Cancer Biology & Medicine
Vol. 17, Issue 4
15 Nov 2020
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Emerging data supporting stromal cell therapeutic potential in cancer: reprogramming stromal cells of the tumor microenvironment for anti-cancer effects
Armel Hervé Nwabo Kamdje, Paul Faustin Seke Etet, Richard Tagne Simo, Lorella Vecchio, Kiven Erique Lukong, Mauro Krampera
Cancer Biology & Medicine Nov 2020, 17 (4) 828-841; DOI: 10.20892/j.issn.2095-3941.2020.0133

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Emerging data supporting stromal cell therapeutic potential in cancer: reprogramming stromal cells of the tumor microenvironment for anti-cancer effects
Armel Hervé Nwabo Kamdje, Paul Faustin Seke Etet, Richard Tagne Simo, Lorella Vecchio, Kiven Erique Lukong, Mauro Krampera
Cancer Biology & Medicine Nov 2020, 17 (4) 828-841; DOI: 10.20892/j.issn.2095-3941.2020.0133
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  • Article
    • Abstract
    • Introduction
    • Pro-tumorigenic effects of stromal cells
    • Stromal cells’ therapeutic potential in cancer
    • Stromal cells follow the program dictated by their microenvironment
    • Some causes of controversies on the roles of stromal cells in cancer
    • Conclusions
    • Acknowledgments
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • References
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Keywords

  • Stromal cells
  • tumorigenic effects
  • anti-cancer effects
  • tumor microenvironment
  • reprogramming

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