tumor microenvironment

Open Access
cGAS–STING pathway activation drives the cold-to-hot tumor transition and sensitizes immunotherapy
Xinru Zhao, Shuai Meng, Hanzeng Cheng, Haixia Yu, Meiting Rong, Chao Zhang, Cien Qiu, Jie Zhang, Chunnuan Wu and Wenxia Zhao

Cancer Biology & Medicine August 2026, 20260058; DOI: https://doi.org/10.20892/j.issn.2095-3941.2026.0058
Open Access
Metabolic regulation of tumor-associated macrophage function and immunotherapy in cancer
Mingyue Zhao, Rui Chen and Ping Gao

Cancer Biology & Medicine June 2026, 23 (6) 810-832; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0626
Open Access
Tumor-resident bacteria in gastrointestinal cancers: from regulatory mechanisms to clinical implications
Ying Zhang, Bingyu Tan, Qianying Zhou, Lixia Xu and Lei Zhou

Cancer Biology & Medicine May 2026, 23 (5) 615-636; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0686
Open Access
Microbial reprogramming of immunogenic cell death: a new paradigm in tumor immunotherapy
Yilin Li, Huiyue Zhang, Yun Feng, Kun Fang, Yue Wang, Yuhang Zhou, Tao Sun and Junnan Xu

Cancer Biology & Medicine May 2026, 23 (5) 657-677; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0769
Open Access
Gut microbiota and pancreatic cancer: tumorigenesis, progression, and clinical applications
Chuxiong Cheng, Jingsong Wang, Jin Xie, Hanlin Yin, Zhihang Xu, Yuqi Xie, Taochen He, Zhenlai Jiang, Yu Wang, Wenchuan Wu, Wenhui Lou, Jie Wang, Liang Liu and Ning Pu

Cancer Biology & Medicine May 2026, 23 (5) 678-702; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0650
Open Access
Design principles of nanomaterials for cancer immunotherapy: a mechanistic framework across the cancer immunity cycle
Yating Bai, Zhihao Lan, Nana Feng, Zhanzhan Zhang and Yang Liu

Cancer Biology & Medicine April 2026, 23 (4) 541-558; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0737
Open Access
Tumor microenvironment-driven natural killer cell diversity: mechanisms and therapeutic opportunities
Yue Duan, Mingzhen Zhou, Xingxian Guo, Tianyu Cao, Yuanyuan Lu and Xiaodi Zhao

Cancer Biology & Medicine April 2026, 20250829; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0829
Open Access
Targeting tumor-infiltrating regulatory T cells based on immunometabolism
Na Li and Dexue Tian

Cancer Biology & Medicine February 2026, 23 (2) 186-200; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0645
Open Access
Coordinated DNA methyltransferase 3A and methyltransferase-like 7A activity reprograms the tumor microenvironment through discoidin domain receptor 1 signaling
Zhengyang Bai, Dan Yang, Jiayi Li, Yaobang Liu, Bin Lian and Jinping Li

Cancer Biology & Medicine January 2026, 23 (1) 107-132; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0261
Open Access
Harnessing the power of cancer-associated fibroblasts to revolutionize pancreatic cancer treatment
Jian Shen, Ruopu Wu, Tao Yin, Qun Wang and Lei Nie

Cancer Biology & Medicine December 2025, 22 (12) 1473-1492; DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0288

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