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EditorialEditorial

Immunosuppressive checkpoint Siglec-15: a vital new piece of the cancer immunotherapy jigsaw puzzle

Xiubao Ren
Cancer Biology & Medicine May 2019, 16 (2) 205-210; DOI: https://doi.org/10.20892/j.issn.2095-3941.2018.0141
Xiubao Ren
1Department of Biotherapy, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer; Key Laboratory of Cancer Prevention and Therapy, Tianjin; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China
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  • For correspondence: rwziyi{at}yahoo.com
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    The balance of Yin and Yang in immunity. (A) The balance of immunity in healthy people. (B) After tumorigenesis, tumor uses various immunosuppressive mechanisms to escape from immune attack. (C) In conventional immunotherapies, excessive immune enhancement can cause autoimmune diseases.

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Cancer Biology and Medicine: 16 (2)
Cancer Biology & Medicine
Vol. 16, Issue 2
1 May 2019
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Immunosuppressive checkpoint Siglec-15: a vital new piece of the cancer immunotherapy jigsaw puzzle
Xiubao Ren
Cancer Biology & Medicine May 2019, 16 (2) 205-210; DOI: 10.20892/j.issn.2095-3941.2018.0141

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Immunosuppressive checkpoint Siglec-15: a vital new piece of the cancer immunotherapy jigsaw puzzle
Xiubao Ren
Cancer Biology & Medicine May 2019, 16 (2) 205-210; DOI: 10.20892/j.issn.2095-3941.2018.0141
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    • Cancer immunotherapy: from enhancement to normalization
    • TCAA: a new member in the arsenal of tumor basic and translational research
    • Discovery of the novel Siglec-15 immune suppressor and its vital role as an immune normalization target
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    • Conflict of interest statement
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  • Multi-cancer early detection: from promise to practice and the next frontier
  • Tumor microenvironment-responsive polymeric nanoparticles for enhanced immunotherapy
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