Clinical Features and Mid-Term and Long-Term Outcomes of Surgical Treatment of 8 Patients with Primary Ventricular Tumors

OBJECTIVE To summarize the clinical features and surgical treatment of primary ventricular tumors.

METHODS Eight patients with primary ventricular tumor, aged 3 to 52 years, underwent surgical treatment. There were 6 males and 2 females. The pathological diagnoses were as follows: multiple left ventricular myxomas In 2 cases: left ventricular rhabdomyoma, fibroma and malignant neurolemmoma In 1 case for each; right ventricular myxoma and malignant neurolemmoma in 1 case for each: intraseptal fibroma In 1 case. The operations were performed through median sternotomy with moderate hypothermic cardiopulmonary bypass in 7 cases; via left anterolateral thoracotomy without extracorporeal circulation In 1 case. Tumors were totally removed In 7 cases and subtotally resected in 1 case.

RESULTS Cardiac arrest after anaesthetization occurred In 1 case with postoperative coma for 10 days. One case died of massive gastro-intestinal hemorrhage postoperatively. Seven cases survived, During a follow-up period of 1 to 21 years, there was no recurrence or metastasis In the 6 cases who received complete tumor resection Including 2 cases with malignant tumor. One case of partial tumor removal had a mild heart murmur without tumor progression. All patients were asymptomatic with cardiac function grade I

CONCLUSION Primary ventricular tumors showed diversity In their histological characteristics. The mid- and long-term outcomes of surgical treatment for primary ventricular tumors appear to be satisfactory.