Review ArticleReview
COX-2 as a potential biomarker and therapeutic target in melanoma
Diana Valentina Tudor, Ioana Bâldea, Mihai Lupu, Teodor Kacso, Eniko Kutasi, Andreea Hopârtean, Roland Stretea and Adriana Gabriela Filip
Cancer Biology & Medicine February 2020, 17 (1) 20-31; DOI: https://doi.org/10.20892/j.issn.2095-3941.2019.0339
Diana Valentina Tudor
1Department of Physiology, University of Medicine and Pharmacy “Iuliu Hațieganu”, Cluj-Napoca 400000, Romania
Ioana Bâldea
1Department of Physiology, University of Medicine and Pharmacy “Iuliu Hațieganu”, Cluj-Napoca 400000, Romania
Mihai Lupu
1Department of Physiology, University of Medicine and Pharmacy “Iuliu Hațieganu”, Cluj-Napoca 400000, Romania
Teodor Kacso
1Department of Physiology, University of Medicine and Pharmacy “Iuliu Hațieganu”, Cluj-Napoca 400000, Romania
Eniko Kutasi
1Department of Physiology, University of Medicine and Pharmacy “Iuliu Hațieganu”, Cluj-Napoca 400000, Romania
Andreea Hopârtean
1Department of Physiology, University of Medicine and Pharmacy “Iuliu Hațieganu”, Cluj-Napoca 400000, Romania
Roland Stretea
1Department of Physiology, University of Medicine and Pharmacy “Iuliu Hațieganu”, Cluj-Napoca 400000, Romania
Adriana Gabriela Filip
1Department of Physiology, University of Medicine and Pharmacy “Iuliu Hațieganu”, Cluj-Napoca 400000, Romania
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In this issue
COX-2 as a potential biomarker and therapeutic target in melanoma
Diana Valentina Tudor, Ioana Bâldea, Mihai Lupu, Teodor Kacso, Eniko Kutasi, Andreea Hopârtean, Roland Stretea, Adriana Gabriela Filip
Cancer Biology & Medicine Feb 2020, 17 (1) 20-31; DOI: 10.20892/j.issn.2095-3941.2019.0339
Jump to section
- Article
- Abstract
- Introduction
- COX-2 pathways in inflammation and cancer
- COX-2 and transcription factors in melanoma
- UV exposure, COX-2 production, and melanogenesis
- COX-2 as a prognostic factor in malignant melanoma
- COX-2 as a target and COX-2 inhibitors in melanoma
- The importance of COX-2 for immunotherapy in melanoma
- Clinical trials that employed COX-2 inhibitors in melanoma
- Conclusions
- Acknowledgments
- Footnotes
- References
- Figures & Data
- References
- Info & Metrics
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