Article Figures & Data
Figures
- 1
Schematic representation of nodal status. NSLN transfer ratio: number of NSLN involved/number of NSLN detected.
- 2
Non-SLN rates when there are 0 to 3 risk factors. Risk factors include: (1) number of positive SLN ≥3; (2) SLN macrometastases; (3) lymphovascular invasion.
Tables
Characteristics Number of lymph nodes Detected SLN Median 3 Range 1–11 Positive SLN Median 1 Range 1–7 Positive NSLN Median 2 Range 1–14 Clinicopathological characteristics Positive non-SLNs, n (%) Negative non-SLNs, n Total χ2 P Gender - - Male 0 1 1 Female 95 (32.2) 200 295 Age (years) 0.147 0.702 <50 45 (31.3) 100 145 ≥50 50 (33.1) 101 151 Mammary gland 0.190 0.663 Left 47 (33.3) 94 141 Right 48 (31.0) 107 155 Location of primary mass 2.739 0.602 Outer upper 42 (37.2) 71 113 Outer under 9 (34.6) 17 26 Upper inner 18 (26.5) 50 68 Lower inner 5 (33.3) 10 15 Other 24 (30.4) 55 79 Multicentric, multifocal 3.842 0.050 Yes 12 (50) 12 24 No 83 (30.5) 189 272 Clinical tumor size 0.528 0.468 T1 52 (30.4) 119 171 ≥T2 43 (34.4) 82 125 Surgery 0.956 0.328 Mastectomy 81 (33.3) 162 243 Breast conversing surgery 14 (26.4) 39 53 Tracer method 1.113 0.573 Blue dye alone 23 (35.4) 42 65 Blue dye + radioisotope 28 (28.0) 72 100 Blue dye + fluorescence 44 (33.6) 87 131 Number of SLN detected 1.917 0.166 1–2 42 (36.8) 72 114 ≥3 53 (29.1) 129 182 Metastatic SLN 20.207 <0.001 1 56 (28.1) 143 199 2 18 (27.3) 48 66 ≥3 21 (67.7) 10 31 SLN transfer ratio
0.003
0.957
<50%
46 (31.9)
98
144
≥50%
49 (32.2)
103
152
SLN 100% positive
0.963
0.327
Yes
19 (38.0)
31
50
No
76 (30.9)
170
246
SLN transfer size
5.132
0.023
ITC
0 (0)
2
2
Micro
8 (17.8)
37
45
Macro
87 (34.9)
162
249
Primary pathological type
0.164
0.686
IDC
90 (32.4)
188
276
Other
5 (27.8)
13
18
Histological grade
1.343
0.719
1
4 (25)
12
16
2
68 (34)
132
200
3
20 (30.0)
47
67
Unclear
3 (23.1)
10
13
ER
0.180
0.671
Negative
12 (35.2)
22
34
Positive
83 (31.7)
179
262
PR
0.037
0.847
Negative
18 (31.0)
40
58
Positive
77 (34.9)
161
238
HER-2
0.023
0.988
Negative
72 (32.0)
153
225
Positive
19 (32.8)
39
58
Critical value
4 (30.8)
9
13
Ki-67
0.545
0.761
<14%
29 (29.9)
68
97
≥14%
62 (32.8)
127
189
Unclear
4 (40.0)
6
10
Molecular classification
0.406
0.939
Luminal A
22 (29.7)
52
74
Luminal B
57 (32.0)
121
178
HER-2
5 (33.3)
10
15
Triple negative
6 (37.5)
10
16
Unclear or unable to classify
5 (38.5)
8
13
Lymph-vascular invasion
11.146 0.004
No
17 (19.8)
69
86
Yes
72 (39.1)
112
184
Unclear
6 (23.1)
20
26
SLN transfer ratio: number of SLN involved/number of SLN detected. Macro: macrometastasis; Micro: micrometastasis; ITC: isolated tumor cells.
