Analysis of up-regulation of DNA-PKcs and its mechanism in human gliomas

Z Zhuang, L Shen, S Zhang, P Qiu - Clinical Oncology and Cancer …, 2010 - Springer
Objective To detect the differences in gene expression of nonhomologous end-joining
pathway including Ku70, Ku80, ERCC4, lig4 and DNA-PKcs between human primary …

Up-regulation of DNA-PKcs and Its Mechanism in Human Glioma

Z Zhuang, L Shen, S Zhang… - Chinese Journal of …, 2010 - pesquisa.bvsalud.org
Objective: To detect the gene expression of Ku70, Ku80, ERCC4, lig4 and DNA-PKcs in non-
homologous end joining pathway in human pdmary glioma tissues and normal brain tissues …

DNA-PKcs expression in hepatoma and normal mouse liver tissues of various developmental stages and its influence on cell proliferation

YC HUANG - Academic Journal of Second Military Medical …, 2010 - pesquisa.bvsalud.org
Objective: To observe the expression of DNA dependent protein kinase catalytic subunit
(DNA-PKcs) in the hepatoma tissues and mouse liver tissues of different developmental …

Expression of DNA-PK in hepato-and cholangio-neoplasms and its significance

ZJ Yu, JG Sui, YQ Ding, ZS Cao, PK Zhou… - Zhonghua gan Zang …, 2004 - europepmc.org
Objective To characterize DNA-PKcs and Ku70 expressions in hepato-and cholangio-
neoplastic tissues and the association with the degree of malignancy and invasiveness of …

Chk2 down-regulation by promoter hypermethylation in human bulk gliomas

H Wang, S Wang, L Shen, Y Chen, X Zhang, J Zhou… - Life sciences, 2010 - Elsevier
AIMS: Gliomas account for 80% of malignant brain tumors. DNA damage response and
subsequent checkpoint control pathways could maintain the integrity of the genome and …

Promoter methylation of DAPK gene in cervical carcinoma

XL Zhao, ZY Meng, YH Qiao… - Ai Zheng= Aizheng …, 2008 - europepmc.org
Methods The promoter methylation of DAPK was investigated with methylation-specific
polymerase chain reaction (MSP) in 52 specimens of cervical cancer, 60 specimens of …

The prognostic value of DAPK1 hypermethylation in gliomas: A site-specific analysis

X Li, J Pu, J Liu, Y Chen, Y Li, P Hou, B Shi… - Pathology-Research and …, 2018 - Elsevier
Background and aims The gene of death associated protein kinase 1 (DAPK1) has been
reported to be methylated in various cancers including gliomas. However, its prognostic …

Cancer Research, Tumor Markers, Clinical Oncology

T Zima - 2007 - karger.com
We analyzed expression status of DKK genes in nine CRC cell lines by RT-PCR. We
analyzed methylation status of DKK genes by methylation-specific PCR (MSP) and bisulfite …

[PDF][PDF] Study of promoter CpG island hypermethylation of cyclindependent kinase inhibitor gene p21waf1/cip1 on some breast carcinoma cell lines

M Alipour, SJ Zargar, S Safarian… - Progress in Biological …, 2013 - pbiosci.ut.ac.ir
The p21 belongs to the CIP/KIP family of CDK inhibitors involved in cell cycle arrest at
specific stages of the cell cycle progression. DNA methylation is the best studied epigenetic …

The relationship between the down-regulation of DNA-PKcs or Ku70 and the chemosensitization in human cervical carcinoma cell line HeLa

X Tian, G Chen, H Xing, D Weng… - Oncology …, 2007 - spandidos-publications.com
The aim of this study was to clarify the function of non-homologous end-joining (NHEJ) in
tumorigenesis and chemoresistance, and to explore the potential of DNA-PK as a target of …