OBJECTIVE The aim of this study was to investigate the correlation between cathepsin D
(Cath-D) and estrogen receptor (ER) expression in breast cancer tissue and to explore the …

The expression of Cathepsin-D (Cath-D), c-erb B-2 and EGFR in breast cancer and its
correlation to lymphatic metastases were studied in 277 cases by immunohistochemical …

Purpose: To assess whether the expression of estrogen-induced protease, cathepsin D,
might facilitate biological subgrouping of patients with breast carcinomas, and accordingly …

Cathepsin D may help in discriminating node-negative breast cancer patients at risk for local-regional
recurrence. - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe PMC …

The concentration of total cathepsin D in cytosols of 199 node negative women with primary
breast cancer in a 10-year retrospective cohort was assayed. Cathepsin D status alone was …

Background: Cellular biomarkers may predict tumor cell behavior in breast cancer. One of
the most paradoxical biomarker in breast cancer is cathepsin D. Patients and methods: The …

Purpose Cathepsin D, a lysosomal protease has been proposed to playa role in the local
invasion and metastatic dissemination in primary breast cancer. Although there are many …

This is a retrospective study on 162 node-negative patients, with both biochemical and
clinical factors being measured for determination of prognostic markers. Steroid receptors …

Background The prognostic significance of Cathepsin D and optimal methodologies to
measure Cathepsin D in breast cancers are controversial. Patients and methods …

Purpose Cathepsin D is a proteolytic enzyme that is normally localized in the lysosomes and
is involved in the malignant progression of breast cancer. There are conflicting results …