OBJECTIVE To observe the effect of phenylacetate on the expression of RNA editing
deaminase ADAR2 mRNA in glioma cells. METHODS Primary glial cells from human brain …

To study the expression of RNA editing deaminases ADAR2 and ADAR3 in different
malignant glioma cell lines and the effect of phenylacetate on the expression of these genes …

Objective To evaluate the differentiation-inducing effect of phenylacetate on pancreatic
carcinoma cells and underlying mechanism of RNA editing deaminase in cell proliferation …

Background RNA editing is catalyzed by adenosine deaminases acting on RNA (ADARs).
ADAR2 is the main enzyme responsible for recoding editing in humans. Adenosine-to …

Since alterations in post-transcriptional events can contribute to the appearance and/or
progression of cancer, we investigated whether RNA editing, catalyzed by the ADAR …

Abstract Adenosine-to-inosine (A-to-I) RNA editing is the most common type of RNA editing
in mammals, and is catalyzed by adenosine deaminases acting on RNA (ADARs). ADAR2 is …

This study was supported by AIRC. Glioblastoma (or grade IV astrocytomas) is a highly
heterogeneous and deadly malignant brain tumor and one of the most incurable form of …

The roles of alternative splicing and RNA editing in gene regulation and transcriptome
diversity are well documented. Adenosine deaminases acting on RNA (ADARs) are …

Tumor occurrence and development is a complicated process. Previous studies confirm that
DNA mutations result in activation of downstream pathways of tumor cells. Recently, studies …

RNA editing, especially A-to-I RNA editing, is a common post-transcriptional modification in
mammals. Adenosine deaminase acting on RNA (ADAR) is a key protein for A-to-I editing …