Cancer immunotherapy has emerged as a promising approach in cancer treatment and is
considered a major advancement after surgical interventions, radiotherapy, chemotherapy …

This paper discusses the role of peptides in cancer therapy with special emphasis on
peptide drugs which are already approved and those in clinical trials. The potential of …

As the nature of the T cell immune response is defined by T cell receptor recognition of small
protein fragments, referred to as peptides, the identification of peptides would lead us to …

Conventional chemotherapeutic drugs have significant limitations. For example, tumors may
develop resistance, cancers may relapse after treatment, and the drugs may induce …

Background: Therapeutic peptides have great potential as anticancer agents owing to their
ease of rational design and target specificity. However, their utility in vivo is limited by low …

Highlights•Peptides from three distinct groups are important for cancer therapy and
diagnostics.•Anticancer peptides are most frequently mimics of natural proteins and …

Several proteins and peptides have therapeutic potential and can be used for cancer
therapy. By binding to cell surface receptors and other indicators uniquely linked with or …

The identification of human tumor-associated antigens has opened new avenues for
immune intervention in cancer. Clinical trials using synthetic peptides that match segments …

A promising new era of cancer therapeutics with agents that inhibit specific growth
stimulatory pathways is finding a new niche in our armamentarium in the war against cancer …

Peptides make up only a fraction of therapeutically beneficial pharmaceutical molecules that
are either in clinical testing or in the market. Despite the initially low number and impact of …