Tumor tissues contain both tumor and non-tumor cells, which include infiltrated immune cells
and stromal cells, collectively called the tumor microenvironment (TME). Single-cell RNA …

Motivation The tumour microenvironment (TME) contains various cells including stromal
fibroblasts, immune and malignant cells, and its composition can be elucidated using single …

Stromal cells are physiologically essential components of the tumor microenvironment
(TME) that mediates tumor development and therapeutic resistance. Development of a …

The stromal compartment of the tumor microenvironment consists of a heterogeneous set of
tissue-resident and tumor-infiltrating cells, which are profoundly moulded by cancer cells. An …

Tumor-associated macrophages (TAMs) are important immune cells in the tumor
microenvironment, and their invasion in tumors is closely related to poor prognosis …

Single-cell level analysis is powerful tool to assess the heterogeneity of cellular components
in tumor microenvironments (TME). In this study, we investigated immune-profiles using the …

Esophageal squamous cell carcinoma (ESCC) is one of the most aggressive malignancies
with complex tumor microenvironment (TME) which has been proven to be associated with …

Tumors are complex ecosystems in which heterogeneous cancer cells interact with their
microenvironment composed of diverse immune, endothelial, and stromal cells. Cancer …

Single-cell RNA-seq (scRNA-seq) is a powerful technique for decoding the complex cellular
compositions in the tumor microenvironment (TME). As previous studies have defined many …

The initiation and progression of tumors are complex. The cancer evolution-development
hypothesis holds that the dysregulation of immune balance is caused by the synergistic …