[HTML][HTML] Downregulation of KCTD12 contributes to melanoma stemness by modulating CD271
W Shen, Y Li, B Li, L Zheng, X Xie, J Le… - Cancer biology & …, 2019 - ncbi.nlm.nih.gov
Objective Cancer metastasis remains the primary cause of cancer-related death worldwide.
In a previous study, we found that levels of BTB/POZ domain-containing protein KCTD12 are …
In a previous study, we found that levels of BTB/POZ domain-containing protein KCTD12 are …
[HTML][HTML] Lentiviral-mediated overexpression of KCTD12 inhibits the proliferation of human uveal melanoma OCM-1 cells
L Luo, J Cui, Z Feng, Y Li, M Wang… - Oncology …, 2017 - spandidos-publications.com
Human potassium channel tetramerization domain containing 12 (KCTD12, also known as
Pfetin) is a member of the KCTD family which consists of 26 members. It has been reported …
Pfetin) is a member of the KCTD family which consists of 26 members. It has been reported …
[HTML][HTML] Identifies KCTD5 as a novel cancer biomarker associated with programmed cell death and chemotherapy drug sensitivity
YX Shi, JH Yan, W Liu, J Deng - BMC cancer, 2023 - Springer
Background More and more studies have demonstrated that potassium channel
tetramerization domain-containing 5 (KCTD5) plays an important role in the development of …
tetramerization domain-containing 5 (KCTD5) plays an important role in the development of …
[HTML][HTML] KCTD12 regulates colorectal cancer cell stemness through the ERK pathway
L Li, T Duan, X Wang, RH Zhang, M Zhang, S Wang… - Scientific reports, 2016 - nature.com
Targeting cancer stem cells (CSCs) in colorectal cancer (CRC) remains a difficult problem,
as the regulation of CSCs in CRC is poorly understood. Here we demonstrated that …
as the regulation of CSCs in CRC is poorly understood. Here we demonstrated that …
KCTD12 promotes G1/S transition of breast cancer cell through activating the AKT/FOXO1 signaling
R Ye, X Kuang, H Zeng, N Shao, Y Lin… - Journal of Clinical …, 2020 - Wiley Online Library
Background Sustaining proliferation is the most fundamental step for breast cancer tumor
genesis. Accelerated proliferation is usually linked to the uncontrolled cell cycle. However …
genesis. Accelerated proliferation is usually linked to the uncontrolled cell cycle. However …
[HTML][HTML] KCTD11 inhibits growth and metastasis of hepatocellular carcinoma through activating Hippo signaling
R Tong, B Yang, H Xiao, C Peng, W Hu, X Weng… - Oncotarget, 2017 - ncbi.nlm.nih.gov
A lack of effective prognostic biomarkers and molecular targets is a serious problem in
hepatocellular carcinoma. KCTD11, reported as a tumor suppressor, are still not well …
hepatocellular carcinoma. KCTD11, reported as a tumor suppressor, are still not well …
[HTML][HTML] KCTD15 deregulation is associated with alterations of the NF-κB signaling in both pathological and physiological model systems
G Smaldone, L Coppola, K Pane, M Franzese… - Scientific Reports, 2021 - nature.com
Like other KCTD proteins, KCTD15 is involved in important albeit distinct biological
processes as cancer, neural crest formation, and obesity. Here, we characterized the role of …
processes as cancer, neural crest formation, and obesity. Here, we characterized the role of …
[HTML][HTML] Contribution of KCTD12 to esophageal squamous cell carcinoma
MR Abbaszadegan, N Taghehchian, L Li, A Aarabi… - BMC cancer, 2018 - Springer
Background It has been shown that the expression of potassium channel tetramerization
domain containing 12 (KCTD12) as a regulator of GABAB receptor signaling is reversely …
domain containing 12 (KCTD12) as a regulator of GABAB receptor signaling is reversely …
[HTML][HTML] KCTD9 inhibits the Wnt/β-catenin pathway by decreasing the level of β-catenin in colorectal cancer
H Yao, D Ren, Y Wang, L Wu, Y Wu, W Wang… - Cell Death & …, 2022 - nature.com
Colorectal cancer (CRC) is the second leading cause of cancer mortality worldwide.
However, the molecular mechanisms underlying CRC progression remain to be further …
However, the molecular mechanisms underlying CRC progression remain to be further …
[HTML][HTML] Suppression of CCT3 inhibits melanoma cell proliferation by downregulating CDK1 expression
W Liu, X Zhang, C Chen, Y Li, C Yang, Z Han… - Journal of …, 2022 - ncbi.nlm.nih.gov
The eukaryotic chaperonin family is vital for cell survival. The dysregulation of chaperonin-
containing TCP-1 subunit 3 (CCT3) is implicated in several types of malignant tumors' …
containing TCP-1 subunit 3 (CCT3) is implicated in several types of malignant tumors' …