[HTML][HTML] Coordinated silencing of the Sp1-mediated long noncoding RNA MEG3 by EZH2 and HDAC3 as a prognostic factor in pancreatic ductal adenocarcinoma

T Han, M Zhuo, C Yuan, X Xiao, J Cui… - Cancer biology & …, 2020 - ncbi.nlm.nih.gov
Objective: Pancreatic ductal adenocarcinoma (PDAC) is a disease with high mortality. Many
so-called “junk” noncoding RNAs need to be discovered in PDAC. The purpose of this study …

[HTML][HTML] Long non-coding RNA MEG3 functions as a tumour suppressor and has prognostic predictive value in human pancreatic cancer

L Ma, F Wang, C Du, Z Zhang, H Guo… - Oncology …, 2018 - spandidos-publications.com
Long non-coding RNA (lncRNA) MEG3 has been demonstrated to be a tumour suppressor
in many malignancies. However, the functional role of MEG3 in pancreatic cancer (PC) is …

Downregulated long noncoding RNA MEG3 is associated with poor prognosis and promotes cell proliferation in gastric cancer

M Sun, R Xia, F Jin, T Xu, Z Liu, W De, X Liu - Tumor Biology, 2014 - Springer
Long noncoding RNAs (lncRNAs) have emerged recently as major players in governing
fundamental biological processes, and many of which are altered in expression and likely to …

Overexpression of long non‐coding RNA MEG3 inhibits proliferation of hepatocellular carcinoma Huh7 cells via negative modulation of miRNA‐664

JH He, ZP Han, JM Liu, JB Zhou… - Journal of cellular …, 2017 - Wiley Online Library
Evidence is accumulating that long non‐coding RNAs (lncRNAs) are involved in human
tumorigenesis and dysregulated in many cancers, including hepatocellular carcinoma …

[HTML][HTML] The biological roles and molecular mechanisms of long non-coding RNA MEG3 in the hallmarks of cancer

L Zhang, F Zhao, W Li, G Song, V Kasim, S Wu - Cancers, 2022 - mdpi.com
Simple Summary MEG3 is a class of lncRNA, which is considered a tumor suppressor. It is
lost or decreased in different biological processes of various human tumors and is closely …

[HTML][HTML] LncRNA meg3 suppresses hepatocellular carcinoma in vitro and vivo studies

Y Zhang, J Liu, Y Lv, C Zhang, S Guo - American journal of …, 2019 - ncbi.nlm.nih.gov
Although abnormal expression of the long non-coding RNA (lncRNA) MEG3 has been
reported in multiple cancer types, the role of MEG3 in the pathobiology of hepatocellular …

Downregulated MEG3 contributes to tumour progression and poor prognosis in oesophagal squamous cell carcinoma by interacting with miR-4261, downregulating …

J Ma, TF Li, XW Han, HF Yuan - Artificial cells, nanomedicine, and …, 2019 - Taylor & Francis
Abstract Long noncoding RNA (lncRNA) MEG3 has been widely reported to be decreased in
a growing list of primary human tumours and play a key role in tumour suppression …

Decreased expression of long noncoding RNA MEG3 affects cell proliferation and predicts a poor prognosis in patients with colorectal cancer

D Yin, Z Liu, E Zhang, R Kong, Z Zhang, R Guo - Tumor Biology, 2015 - Springer
Colorectal cancer (CRC) remains an important public health problem in the world. Long
noncoding RNA (lncRNA) is an RNA molecular that is longer than 200 nucleotides and …

[HTML][HTML] Long noncoding RNA MEG3 suppresses liver cancer cells growth through inhibiting β-catenin by activating PKM2 and inactivating PTEN

Q Zheng, Z Lin, J Xu, Y Lu, Q Meng, C Wang… - Cell death & …, 2018 - nature.com
Abstract Maternally expressed gene 3 (MEG3) encodes an lncRNA which is suggested to
function as a tumor suppressor and has been showed to involve in a variety of cancers …

[HTML][HTML] miR-122-mediated translational repression of PEG10 and its suppression in human hepatocellular carcinoma

YC Shyu, TL Lee, MJ Lu, JR Chen, RN Chien… - Journal of translational …, 2016 - Springer
Background Hepatocellular carcinoma (HCC), a primary liver malignancy, is the most
common cancer in males and fourth common cancer in females in Taiwan. HCC patients …