Growth inhibiton of human breast cancer cell line MDA-MB-231 by rosiglitazone through activation of PPARγ

T Zhang, Q Zhang, D Chen, J Jiang, Q Zhou - Chinese Journal of Clinical …, 2008 - Springer
Objective To investigate the anti-proliferative effect of rosiglitazone and its relationship to
peroxisome proliferator-activated receptor γ (PPARγ) in human breast cancer cell line MDA …

Inhibition of the breast cancer by PPARγ agonist pioglitazone through JAK2/STAT3 pathway.

XX Jiao, SY Lin, SX Lian, YR Qiu, ZH Li… - …, 2020 - search.ebscohost.com
Breast cancer, especially triple-negative breast cancer, is one of the deadliest cancers in
women. To date, there is a lack of a good therapeutic regimen for it. PPARγ has been …

Anti‐proliferative effect of rosiglitazone in the human T‐lymphocyte leukaemia cell line Jurkat cells

R Wei, F Yu, J Yang, H Gao, H Wang… - Cell Biology …, 2018 - Wiley Online Library
Peroxisome proliferator‐activated receptor γ (PPARγ) is expressed in various types of
human cancer cells including leukaemia cells, and activation of PPARγ can inhibit cancer …

Effect of PPAR Partial Agonist, GQ‐16, on Viability of Breast Cancer Cells in Culture

APB Ferreira, MS Coelho, AA Amato… - The FASEB …, 2017 - Wiley Online Library
Breast cancer (BC) is the most frequent cancer in women around the world. Tumor cells
have several mechanisms of resistance to chemotherapy treatment, so the relevance of …

[HTML][HTML] Effects of PPARγ agonistrosiglitazone on human retinoblastoma cell in vitro and in vivo

X Cao, L He, Y Li - … journal of clinical and experimental pathology, 2015 - ncbi.nlm.nih.gov
The aim of the study was to evaluate the antitumor effects of the PPARγ agonist rosiglitazone
on the human retinoblastoma. The cell biological behavior was detected, specifically, the …

[HTML][HTML] Rosiglitazone inhibits metastasis development of a murine mammary tumor cell line LMM3

G Magenta, X Borenstein, R Rolando, MA Jasnis - BMC cancer, 2008 - Springer
Background Activation of peroxisome proliferator-activated receptors γ (PPARγ) induces
diverse effects on cancer cells. The thiazolidinediones (TZDs), such as troglitazone and …

Expression of PPAR-gamma in human hilar bile duct carcinoma cell line QBC939 and the effects of PPAR-Y activated by its ligand on the growth of QBC939

W Cheng, NS Cheng, XZ Xiong, QJ Xia… - Sichuan da xue xue …, 2006 - europepmc.org
Objective To explore the expression of Peroxisome Proliferator-activated Receptor-gamma
(PPAR-gamma) in QBC939 and the effects of PPAR-gamma activated by its ligand …

Peroxisome proliferator-activated receptor γ (PPAR-γ) agonist rosiglitazone (RGZ) inhibits HL-60 cell growth by induction of apoptosis

JJ Liu, Y Zhang, RZ Xiao, DJ Lin - Laboratory Medicine, 2009 - academic.oup.com
Objective To investigate the apoptotic effects of peroxisome proliferator-activated receptor γ
(PPAR-γ) agonist rosiglitazone (RGZ) on leukemia HL-60 cells. Methods Cell apoptosis was …

[HTML][HTML] Rosiglitazone sensitizes MDA-MB-231 breast cancer cells to anti-tumour effects of tumour necrosis factor-α, CH11 and CYC202

M Mody, N Dharker, M Bloomston… - Endocrine-Related …, 2007 - erc.bioscientifica.com
Peroxisome proliferator-activated receptor-γ (PPARγ) is a member of the nuclear hormone
superfamily and has multiple endogenous and pharmacological ligands, including 15-deoxy …

Pilot study of rosiglitazone therapy in women with breast cancer: effects of short-term therapy on tumor tissue and serum markers

LD Yee, N Williams, P Wen, DC Young, J Lester… - Clinical Cancer …, 2007 - AACR
Purpose: Peroxisome proliferator-activated receptor γ (PPARγ) is a steroid nuclear receptor
that is activated by natural compounds such as specific fatty acids and synthetic drugs such …