[HTML][HTML] Expression of angiotensin II and aldosterone in radiation-induced lung injury

S Cao, R Wu - Cancer Biology & Medicine, 2012 - ncbi.nlm.nih.gov
Objective Radiation-induced lung injury (RILI) is the most common, dose-limiting
complication in thoracic malignancy radiotherapy. Considering its negative impact on …

Targeting the renin–angiotensin system combined with an antioxidant is highly effective in mitigating radiation-induced lung damage

J Mahmood, S Jelveh, A Zaidi, SR Doctrow… - International Journal of …, 2014 - Elsevier
Purpose To investigate the outcome of suppression of the renin angiotensin system using
captopril combined with an antioxidant (Eukarion [EUK]-207) for mitigation of radiation …

[HTML][HTML] Protection against acute radiation-induced lung injury: a novel role for the anti-angiogenic agent Endostar

K Zhang, S Yang, Y Zhu, A Mo… - Molecular medicine …, 2012 - spandidos-publications.com
Radiotherapy is commonly used to treat thoracic malignancies, but often causes severe lung
injury. Currently there are no effective protective strategies against radiation‑induced lung …

Temporal onset of hypoxia and oxidative stress after pulmonary irradiation

K Fleckenstein, L Zgonjanin, L Chen, Z Rabbani… - International Journal of …, 2007 - Elsevier
Purpose: To investigate the temporal onset of hypoxia following irradiation, and to show how
it relates to pulmonary vascular damage, macrophage accumulation, and the production of …

Renin-Angiotensin system suppression mitigates experimental radiation pneumonitis

SN Ghosh, R Zhang, BL Fish, VA Semenenko… - International Journal of …, 2009 - Elsevier
PURPOSE: To find the mitigators of pneumonitis induced by moderate doses of thoracic
radiation (10–15 Gy). METHODS AND MATERIALS: Unanesthetized WAG/RijCmcr female …

[HTML][HTML] Changes in serum transforming growth factor-beta concentration as a predictive factor for radiation-induced lung injury onset in radiotherapy-treated patients …

Y Seto, Y Kaneko, T Mouri, D Shimizu… - Translational Lung …, 2022 - ncbi.nlm.nih.gov
Background Radiation-induced lung injury (RILI) occurs after chest radiation therapy, which
ranges from acute radiation pneumonia to subsequent radiation pulmonary fibrosis …

[HTML][HTML] Genetic variations in TGFβ1, tPA, and ACE and radiation-induced thoracic toxicities in patients with non–small-cell lung cancer

VL Ellingrod, M Schipper, KA Stringer, X Cai… - Journal of Thoracic …, 2013 - Elsevier
Introduction We hypothesized that radiation-induced thoracic toxicity (RITT) of the lung,
esophagus and pericardium share a similar mechanism, and aimed to examine whether …

[HTML][HTML] Effect of angiotensin II on irradiation exacerbated decompression sickness

JF Fan, YK Wang, M Liu, GS Liu, TJ Min, RY Chen… - Scientific Reports, 2023 - nature.com
In some complicated situations, decompression sickness (DCS) combined with other
injuries, such as irradiation, will seriously endanger life safety. However, it is still unclear …

Radiation-induced hypoxia may perpetuate late normal tissue injury

Z Vujaskovic, MS Anscher, QF Feng… - International Journal of …, 2001 - Elsevier
Purpose: The purpose of this study was to determine whether or not hypoxia develops in rat
lung tissue after radiation. Methods and Materials: Fisher-344 rats were irradiated to the right …

[PDF][PDF] Irradiation induces a biphasic expression of pro-inflammatory cytokines in the lung

CE Rübe, F Wilfert, J Palm, J König… - Strahlentherapie und …, 2004 - academia.edu
Background and Purpose: The precise pathophysiological mechanisms of radiation-induced
lung injury are poorly understood, but have been shown to correlate with dysregulation of …