[HTML][HTML] Genetic and molecular changes in ovarian cancer

RL Hollis, C Gourley - Cancer biology & medicine, 2016 - ncbi.nlm.nih.gov
Epithelial ovarian cancer represents the most lethal gynecological malignancy in the
developed world, and can be divided into five main histological subtypes: high grade …

[HTML][HTML] Molecular abnormalities in ovarian cancer subtypes other than high-grade serous carcinoma

CB Gilks - Journal of oncology, 2010 - hindawi.com
Ovarian cancer is the fifth leading cause of cancer death in women in North America, and
approximately two-thirds of cases of ovarian cancer are of high-grade serous type. The …

Ovarian cancer and the evolution of subtype classifications using transcriptional profiling

DP Cook, BC Vanderhyden - Biology of reproduction, 2019 - academic.oup.com
Ovarian cancer is a complex disease with multiple subtypes, each having distinct
histopathologies and variable responses to treatment. This review highlights the …

[HTML][HTML] Epithelial ovarian cancer: the molecular genetics of epithelial ovarian cancer

J Krzystyniak, L Ceppi, DS Dizon, MJ Birrer - Annals of Oncology, 2016 - Elsevier
Background Epithelial ovarian cancer (EOC) remains one of the leading causes of cancer-
related deaths among women worldwide, despite gains in diagnostics and treatments made …

Molecular characterization of ovarian cancer by gene-expression profiling

C Gomez-Raposo, M Mendiola, J Barriuso… - Gynecologic …, 2010 - Elsevier
Ovarian cancer is the second most common gynecologic malignancy, and represents the
fifth most common cause of cancer death in women in the United States. The age at …

[HTML][HTML] Molecular characterization of epithelial ovarian cancer: implications for diagnosis and treatment

V Rojas, KM Hirshfield, S Ganesan… - International journal of …, 2016 - mdpi.com
Epithelial ovarian cancer is a highly heterogeneous disease characterized by multiple
histological subtypes. Molecular diversity has been shown to occur within specific …

Origins based clinical and molecular complexities of epithelial ovarian cancer

T Muinao, M Pal, HPD Boruah - International journal of biological …, 2018 - Elsevier
Ovarian cancer is the most lethal of all common gynaecological malignancies in women
worldwide. Ovarian cancer comprises of> 15 distinct tumor types and subtypes …

[HTML][HTML] Molecular characteristics and clinical behaviour of epithelial ovarian cancers

RL Hollis - Cancer letters, 2023 - Elsevier
Ovarian carcinoma (OC) is an umbrella term for multiple distinct diseases (histotypes), each
with their own developmental origins, clinical behaviour and molecular profile. Accordingly …

[HTML][HTML] Clinical interest of combining transcriptomic and genomic signatures in high-grade serous ovarian cancer

Y Kieffer, C Bonneau, T Popova, R Rouzier… - Frontiers in …, 2020 - frontiersin.org
High-grade serous ovarian cancer is one of the deadliest gynecological malignancies and
remains a clinical challenge. There is a critical need to effectively define patient stratification …

Validating the impact of a molecular subtype in ovarian cancer on outcomes: a study of the OVCAD Consortium

D Pils, G Hager, D Tong, S Aust, G Heinze… - Cancer …, 2012 - Wiley Online Library
Most patients with epithelial ovarian cancer (EOC) are diagnosed at advanced stage and
have a poor prognosis. However, a small proportion of these patients will survive, whereas …