Objective To investigate the active expression of pepsinogen C (PGC) and its value in
detection of precancerous diseases and gastric cancer. Methods Immunohistochemistry was …

Objective To investigate the dynamic expression of pepsinogen C (PGC) and its value in
detection of precursor and gastric cancer. Methods Immunohistochemistry was used to …

Objective To estimate the practical values of pepsinogen C (PGC) dynamic expression and
the levels of serum pepsinogens in gastric cancer screening and diagnosis. Methods 129 …

AIM: To investigate the relationship between the expression of pepsinogen C (PGC) and
gastric cancer, precancerous diseases, and Helicobacter pylori (H pylori) infection …

Pepsinogen C (PGC) belongs to the aspartic protease family and is secreted by gastric chief
cells. PGC could be activated to pepsin C and digests polypeptides and amino acids, but as …

Background: In this study we evaluated the expression and clinical significance of
pepsinogen C, an aspartic proteinase involved in the digestion of proteins in the stomach, in …

Gastric tumorigenesis is a multistep process initiated by chronic superficial gastritis (SG),
followed by atrophic gastritis (AG), then intestinal metaplasia (IM), and finally by dysplasia …

Methods PGC insertion/deletion polymorphism was evaluated by PCR, followed by direct
DNA sequencing in 493 cases of GC, atrophic gastritis (AG), gastric erosion ulcer (GEU) and …

Objective Toinvestigatethepossibilityandquantitativer… (PG) usedas the screening marker of
gastric cancer by detecting serum pepsinogen level in different gastric mucous pathologic …

Abstract Background Pepsinogen C (PGC) is expressed in chief cells, fundic mucous neck
cells, and pyloric gland cells of gastric epithelium and also in breast, prostate, lung, and …