[HTML][HTML] Epigenetics of cutaneous T-cell lymphoma: biomarkers and therapeutic potentials

P Lai, Y Wang - Cancer Biology & Medicine, 2021 - ncbi.nlm.nih.gov
Cutaneous T-cell lymphomas (CTCLs) are a heterogeneous group of skin-homing non-
Hodgkin lymphomas. There are limited options for effective treatment of patients with …

[HTML][HTML] Epigenetics in the pathogenesis and treatment of cutaneous T-cell lymphoma

P Zhang, M Zhang - Frontiers in Oncology, 2021 - frontiersin.org
Cutaneous T-cell lymphomas (CTCLs) comprise a group of heterogeneous diseases
involving malignant T cells. The pathogenesis and etiology of CTCL are still unclear …

[HTML][HTML] Epigenetics of cutaneous T-cell lymphomas

N Hara, Y Sawada - International Journal of Molecular Sciences, 2022 - mdpi.com
Epigenetic modifications rarely occur in isolation (as single “epigenetic modifications”). They
usually appear together and form a network to control the epigenetic system. Cutaneous …

[HTML][HTML] Novel biomarkers, dysregulated epigenetics, and therapy in cutaneous T-cell lymphoma

HK Wong - Discovery medicine, 2013 - discoverymedicine.com
Cutaneous T cell lymphomas (CTCL) are a diverse group of lymphoid malignancies that
develop in the skin. The most common variants are mycosis fungoides (MF) and Sezary …

Epigenetic Profiling of Cutaneous T-Cell Lymphoma: Promoter Hypermethylation of Multiple Tumor Suppressor Genes Including BCL7a, PTPRG, and p73

R Van Doorn, WH Zoutman, R Dijkman… - Journal of Clinical …, 2005 - ascopubs.org
Purpose To analyze the occurrence of promoter hypermethylation in primary cutaneous T-
cell lymphoma (CTCL) on a genome-wide scale, focusing on epigenetic alterations with …

[HTML][HTML] Molecular pathogenesis of Cutaneous T cell Lymphoma: Role of chemokines, cytokines, and dysregulated signaling pathways

K Patil, S Kuttikrishnan, AQ Khan, F Ahmad… - Seminars in Cancer …, 2022 - Elsevier
Cutaneous T cell lymphomas (CTCLs) are a heterogeneous group of lymphoproliferative
neoplasms that exhibit a wide spectrum of immune-phenotypical, clinical, and …

Genetic and epigenetic insights into cutaneous T-cell lymphoma

CP Tensen, KD Quint… - Blood, The Journal of the …, 2022 - ashpublications.org
Primary cutaneous T-cell lymphomas (CTCLs) constitute a heterogeneous group of non-
Hodgkin T-cell lymphomas that present in the skin. In recent years, significant progress has …

[HTML][HTML] Update on biology of cutaneous T-cell lymphoma

ZH Phyo, S Shanbhag, S Rozati - Frontiers in oncology, 2020 - frontiersin.org
Cutaneous T cell lymphomas (CTCL) comprise of a heterogeneous group of non-Hodgkin
lymphomas derived from skin-homing T cells. Variation in clinical presentation and lack of …

Epigenetic therapy and dermatologic disease: moving beyond CTCL

JS Mervis, JS McGee - Journal of Dermatological Treatment, 2019 - Taylor & Francis
The epigenetic regulation of gene expression is accomplished primarily through DNA
methylation, histone modification, and gene silencing via the action of microRNAs. While …

[HTML][HTML] Single-cell heterogeneity of cutaneous T-cell lymphomas revealed using RNA-Seq technologies

K Rassek, K Iżykowska - Cancers, 2020 - mdpi.com
Cutaneous T-cell lymphomas (CTCLs) represent a large, heterogeneous group of non-
Hodgkin lymphomas that primarily affect the skin. Among multiple CTCL variants, the most …