[HTML][HTML] Cancer-educated neutrophils promote lung cancer progression via PARP-1-ALOX5-mediated MMP-9 expression
L Han, Y Chen, N Huang, X Zhou, Y Lv… - Cancer Biology & …, 2024 - ncbi.nlm.nih.gov
Objective: Neutrophils are one of the most predominant infiltrating leukocytes in lung cancer
tissues and are associated with lung cancer progression. How neutrophils promote lung …
tissues and are associated with lung cancer progression. How neutrophils promote lung …
[HTML][HTML] Tumor associated neutrophils governs tumor progression through an IL-10/STAT3/PD-L1 feedback signaling loop in lung cancer
S Zhang, L Sun, J Zuo, D Feng - Translational Oncology, 2024 - Elsevier
Tumor-associated neutrophils (TANs) can exist in either a pro-inflammatory or an anti-
inflammatory state, known as N1 and N2, respectively. Anti-inflammatory TANs have been …
inflammatory state, known as N1 and N2, respectively. Anti-inflammatory TANs have been …
[HTML][HTML] Aspirin-triggered resolvin D1 reduces proliferation and the neutrophil to lymphocyte ratio in a mutant KRAS-driven lung adenocarcinoma model
Simple Summary Aspirin-triggered resolvin D1 (AT-RvD1) is biosynthesised by leukocytes
as a mechanism to resolve inflammation during infection and/or injury. Emerging studies …
as a mechanism to resolve inflammation during infection and/or injury. Emerging studies …
[HTML][HTML] Multiple Death Pathways of Neutrophils Regulate Alveolar Macrophage Proliferation
X Gao, W Zhang, N Zhang, Q Yu, J Su, K Wang… - Cells, 2022 - mdpi.com
Alveolar macrophage (AM) proliferation and self-renewal play an important role in the lung
tissue microenvironment. However, the impact of immune cells, especially the neutrophils …
tissue microenvironment. However, the impact of immune cells, especially the neutrophils …
[HTML][HTML] Tumor-associated neutrophils stimulate T cell responses in early-stage human lung cancer
EB Eruslanov, PS Bhojnagarwala… - The Journal of …, 2014 - Am Soc Clin Investig
Infiltrating inflammatory cells are highly prevalent within the tumor microenvironment and
mediate many processes associated with tumor progression; however, the contribution of …
mediate many processes associated with tumor progression; however, the contribution of …
[HTML][HTML] Emerging and multifaceted role of neutrophils in lung cancer
It has long been recognized that cigarette smoking is a shared risk factor for lung cancer and
the debilitating lung disease, chronic obstructive pulmonary disease (COPD). As the severity …
the debilitating lung disease, chronic obstructive pulmonary disease (COPD). As the severity …
[HTML][HTML] Single-cell RNA sequencing uncovered the involvement of an endothelial subset in neutrophil recruitment in chemically induced rat pulmonary inflammation
H Huang, Y Yang, T Song, Y Yang, Y Zhu… - … Journal of Medical …, 2022 - ncbi.nlm.nih.gov
There is growing support for the notion that chronic inflammation contributes to lung
tumorigenesis, but the molecular and cellular basis underlying the protumorigenic effects of …
tumorigenesis, but the molecular and cellular basis underlying the protumorigenic effects of …
[HTML][HTML] PLAG exerts anti-metastatic effects by interfering with neutrophil elastase/PAR2/EGFR signaling in A549 lung cancer orthotopic model
GT Kim, KW Hahn, SY Yoon, KY Sohn, JW Kim - Cancers, 2020 - mdpi.com
The effectiveness of chemotherapy and radiotherapy to treat lung cancer is limited because
of highly metastatic nature. Novel strategies and drugs to attenuate metastatic activity are …
of highly metastatic nature. Novel strategies and drugs to attenuate metastatic activity are …
[PDF][PDF] Tumor-associated neutrophils show phenotypic and functional divergence in human lung cancer
S Saha, SK Biswas - Cancer cell, 2016 - cell.com
Studies in murine cancer models have demonstrated the phenotypic and functional
divergence of neutrophils; however, their role in pro-or anti-tumor responses in human …
divergence of neutrophils; however, their role in pro-or anti-tumor responses in human …
[Corrigendum] Neutrophils in cancer development and progression: Roles, mechanisms, and implications
X Zhang, W Zhang, X Yuan, M Fu… - … Journal of Oncology, 2017 - spandidos-publications.com
116. Chen L, Li Q, Zhou XD, Shi Y, Yang L, Xu SL, Chen C, Cui Yh, Zhang X and Bian XW:
Increased pro-angiogenic factors, infiltrating neutrophils and CD163 (+) macrophages in …
Increased pro-angiogenic factors, infiltrating neutrophils and CD163 (+) macrophages in …