Interaction between colon cancer cells and human liver sinusoidal endothelial cells promotes liver metastasis of tumor cells

L Sun, S Li, L Yu, L Sun, L Han, T Liu, Z Yang… - Clinical Oncology and …, 2011 - Springer
Objective To investigate the effect of co-culture between colon cancer cells (SW1116) and
human liver sinusoidal endothelial cells (HLSECs) on cancer cell metastasis, and to provide …

Phenotypic and functional differences between human liver cancer endothelial cells and liver sinusoidal endothelial cells

LQ Wu, WJ Zhang, JX Niu, LY Ye, ZH Yang… - Journal of vascular …, 2007 - karger.com
Abstract Background/Aims: The phenotypic and functional characteristics of microvascular
endothelial cells derived from human liver cancer (HLCEC) were analyzed in vitro and …

Intracellular gap formation of the liver sinusoidal endothelial cells facilitates the liver metastasis ability of cancer cells

TH Hoang, M Sato-Matsubara, Y Hideto, T Matsubara… - Cancer Research, 2021 - AACR
Engraftment of cancer cells to liver pre-metastatic niches and their subsequent growth
requires complex interaction with liver sinusoidal endothelial cells (LSECs). Intracellular gap …

Differential motility stimulation but not growth stimulation or adhesion of metastatic human colorectal carcinoma cells by target organ-derived liver sinusoidal …

H Sawada, H Wakabayashi, A Nawa, E Mora… - Clinical & experimental …, 1996 - Springer
Liver is the most common distant metastatic site for colorectal cancers and when blood-
borne colorectal cancer cells reach the liver, they first encounter hepatic capillary and …

[HTML][HTML] The role of liver sinusoidal endothelial cells in cancer liver metastasis

M Yang, C Zhang - American Journal of Cancer Research, 2021 - ncbi.nlm.nih.gov
Liver sinusoidal endothelial cells (LSECs) are the gatekeeper cells in the liver, contributing
critical roles in liver physiological and pathological changes. Factors such as dietary …

Liver sinusoidal endothelial cell ICAM-1 mediated tumor/endothelial crosstalk drives the development of liver metastasis by initiating inflammatory and angiogenic …

A Benedicto, A Herrero, I Romayor, J Marquez… - Scientific reports, 2019 - nature.com
The prometastatic stroma generated through tumor cells/host cells interaction is critical for
metastatic growth. To elucidate the role of ICAM-1 on the crosstalk between tumor and …

Angiogenesis of liver metastases: role of sinusoidal endothelial cells

P Gervaz, B Scholl, C Mainguene, S Poitry… - Diseases of the colon & …, 2000 - Springer
PURPOSE: Tumor-induced angiogenesis requires migration and remodeling of endothelial
cells derived from pre-existing blood vessels. Vascular endothelial growth factor is the …

Liver sinusoidal endothelial cell ICAM-1 mediated tumor/endothelial crosstalk drives the development of liver metastasis by initiating inflammatory and angiogenic …

A Benedicto García, A Herrero, I Romayor Arredondo… - 2019 - addi.ehu.es
The prometastatic stroma generated through tumor cells/host cells interaction is critical for
metastatic growth. To elucidate the role of ICAM-1 on the crosstalk between tumor and …

Proof of prometastatic niche induction by hepatic stellate cells

C Eveno, P Hainaud, A Rampanou, P Bonnin… - journal of surgical …, 2015 - Elsevier
Background An interaction between tumor cells and the microenvironment, as well as the
development of angiogenesis, are required to form liver metastases (LMs). Material and …

[HTML][HTML] SK-Hep1: not hepatocellular carcinoma cells but a cell model for liver sinusoidal endothelial cells

Y Tai, JH Gao, C Zhao, H Tong, SP Zheng… - … journal of clinical and …, 2018 - ncbi.nlm.nih.gov
SK-Hep1 cells serve as a cell model of hepatocellular carcinoma and hepatocyte biology.
However, SK-Hep1 cells are markedly different from normal hepatocytes and other …