The Wnt/β-catenin signaling pathway regulates many aspects of tumor biology, and many
studies have focused on the role of this signaling pathway in tumor cells. However, it is now …

Simple Summary The response rate to immune checkpoint inhibitor (ICI) monotherapy in
hepatocellular carcinoma (HCC) is as low as 20%; therefore, it is important to identify the …

Hepatocellular carcinoma (HCC) is a significant global health concern which requires
multidisciplinary approaches in its management. However, apart from surgical resection of …

Liver cancers cause a high rate of death worldwide and hepatocellular carcinoma (HCC) is
considered as the most common primary liver cancer. HCC remains a challenging disease …

Hepatocellular carcinoma (HCC) is a major cause of cancer death worldwide. As in many
other types of cancer, aberrant activation of the canonical Wnt/β-catenin signaling pathway …

Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related death
worldwide. However, targeted therapies are still at their beginning for the treatment of this …

Liver cancer is among the leading global healthcare issues associated with high morbidity
and mortality. Liver cancer consists of hepatocellular carcinoma (HCC), cholangiocarcinoma …

The WNT/β-catenin signaling pathway is a highly conserved and tightly controlled molecular
mechanism that regulates embryonic development, cellular proliferation and differentiation …

Wnt/β‐catenin signaling is indispensable for many biological processes, including
embryonic development, cell cycle, inflammation, and carcinogenesis. Aberrant activation of …

Simple Summary Human primary liver cancers have a poor prognosis. At present, there are
limited treatment alternatives, and to understand the molecular aspects of liver …