Objective: Our aim was to test the hypothesis that fatty acid synthase (FASN) expression
contributes to radioresistance of nasopharyngeal carcinoma (NPC) cells and that inhibiting …

Fatty acid synthase (FASN) is overexpressed in many human cancers and associated with
poor prognosis. However, the role of FASN in nasopharyngeal carcinoma (NPC) has not …

Fatty acid synthase (FASN) is the key enzyme required for the de novo synthesis of long‑
chain fatty acids. FASN has been observed to be overexpressed in the majority of cancer …

Fatty acid synthase (Fasn) is the key metabolic enzyme that accounts for the terminal
catalytic step in fatty acid synthesis, which is hyperactivated in various tumors. In this study …

Fatty acid synthase (FASN) promotes tumor progression in multiple cancers. In this study, we
comprehensively examined the expression, prognostic significance, and promoter …

Fatty acid synthase–associated protein with death domain (FADD) is a key adaptor protein
that bridges a death receptor (eg, death receptor 5) to caspase 8 to form the death-inducing …

Fibroblast growth factor receptor 3 (FGFR3) belongs to a family of receptor tyrosine kinases
that control cell proliferation, differentiation, and survival. Aberrant activation of FGFR3 via …

Fatty Acid Desaturase-1 (FADS1) or delta 5 desaturase (D5D) is a rate-limiting enzyme
involved in the biosynthesis of long-chain polyunsaturated fatty acids (LC-PUFAs), ie …

Hypoxic resistance is the main obstacle to radiotherapy for laryngeal carcinoma. Our
previous study indicated that hypoxia‐inducible factor 1α (HIF‐1α) and glucose transporter 1 …

Fatty acid synthase (FASN) has been shown to be selectively up‐regulated in cancer cells to
drive the development of cancer. However, the role and associated mechanism of FASN in …