Objective To assess the effect of 17β-estradiol (E 2) on cell proliferation, cell invasiveness
and its regulation of MTA3, Snail and matrix metalloproteinase 2 (MMP-2) expression in the …

OBJECTIVE.: The transcription factor Snail, which is implicated in the triggering of epithelial-
mesenchymal transitions (EMT), plays an important role in adhesion, invasion and …

OBJECTIVE: Despite evidence that oestrogen may play an important role in the
carcinogenesis of cervical cancer, its action and mechanism in cervical cancer invasion are …

Ovarian clear cell adenocarcinoma (OCCA) is an aggressive ovarian malignancy with a
poor prognosis. The role of estrogen receptor β (ERβ) in the development of OCCA remains …

It is well known that the functions of reproductive organs are regulated by sex steroids and
their receptors and it is hypothesized that the progression of neoplasms that originate from …

Objective To study the effect of 17-beta estradiol on the growth of the epithelial ovarian
carcinoma cell lines in vitro. Methods The proliferative capacity of the ovarian carcinoma cell …

Tumorigenesis is a multistep process involving dysregulated cell growth and metastasis.
Considerable evidence implicates a mitogenic action of estrogen in early ovarian …

Objective To evaluate the effects of 2-methoxyestradiol (2-ME (2)) on human cervical cancer
HeLaS3 cells and cervical cancer xenografts. Methods Cell proliferation assay and cell cycle …

Purpose: The effects of reproductive hormones on ovarian cancer growth are not well
understood. Here, we examined the effects of estrous cycle variation and specific …

Objective: To investigate the expression of matrix metalloproteinase-9 (MMP-9) gene in
cancer cells induced by adhesion with fibronectin and the underlying mechanism of cell …