Analysis of cardiotoxicity from rh-endostatin therapy combined with chemotherapy

J Qin, P Zhang, X Qian, A Li, R Luo, D Xu - Chinese Journal of Clinical …, 2008 - Springer
Objective To evaluate the cardotoxicity from recombinant human endostatin (rh-endostatin)
combined with chemotherapy. Methods A total of 12 cancer patients treated with …

Assessment of the cardiotoxicity of recombinant human endostatin using myocardial biochemical markers in cancer patients

J Qin, PH Zhang, XY Qian, SJ Kang… - … Fang yi ke da xue xue …, 2008 - europepmc.org
Objective To evaluate the value of the myocardial biochemical markers including creatine
kinase MB isoenzyme (CK-MB), cardiac isoform of Tropnin-T (cTnT) and N-termimal pro …

Recombinant human endostatin-associated acute left heart failure

Q Jing, Q Xinyu, L Rougcheng - Clinical Oncology, 2008 - clinicaloncologyonline.net
Sir d A 72-year-old female patient with stage IV adenocarcinoma of the lung was treated with
recombinant human endostatin (rh-endostatin) combined with gemcitabine. The patient …

Tolerance and pharmacokinetics of recombinant human endostatin administered as single-dose or multiple-dose infusions in patients with advanced solid tumors: A …

X Wang, Y Shi, Y Jia, W Zhao, L Zhang… - … in Cancer Research …, 2021 - journals.sagepub.com
Objective: This study aimed to investigate the tolerance and pharmacokinetic characteristics
of recombinant human endostatin (rh-endostatin) administered as single-dose or multiple …

A randomized phase II study of recombinant human endostatin plus gemcitabine/cisplatin compared with gemcitabine/cisplatin alone as first-line therapy in advanced …

X Zhao, K Mei, X Cai, J Chen, J Yu, C Zhou… - Investigational new drugs, 2012 - Springer
Purpose Studies indicate that recombinant human endostatin (rh-endostatin) can inhibit
tumor endothelial cell proliferation, angiogenesis, and tumor growth. This study assessed …

Recombinant human endostatin combined with navelbine and cisplatin in first line treatment of advanced non-small cell lung cancer

YD DAI - Tumor, 2011 - pesquisa.bvsalud.org
Objective: To investigate the short-term efficacy and safety of recombinant human endostatin
YH-16 combined with navelbine and cisplatin in the first line treatment of advanced non …

Efficacy and safety of human recombinant endostatin plus pemetrexed and cisplatin in the treatment of advanced non-small cell lung cancer

Y Peng, G Zhang - Chinese Journal of General Practitioners, 2013 - pesquisa.bvsalud.org
To explore the efficacy and safety of human recombinant endostatin (rh-endostatin) plus
pemetrexed and cisplatin in the treatment of advanced non-small cell lung cancer (NSCLC) …

Phase Ⅱ clinical trial of homemade human rh-endostatin in the treatment of patients with stage Ⅲb-Ⅳ non-small cell lung cancer

SHI Heling, XU Liyan, LIU Zhe - Zhongguo Fei Ai Za Zhi, 2004 - search.proquest.com
目的 观察重组人血管内皮抑制素 (YH-16) 联合 NP 方案 (去甲长春花碱 NVB+ 顺铂 DDP)
治疗晚期非小细胞肺癌的疗效和安全性, 并与 NP 方案比较. 方法 18 例 ⅢB~ Ⅳ 期 NSCLC …

Reversal effect of recombinant human Endostatin on cisplatin resistance in A549/DDP human lung adenocarcinoma cells in vitro

Y Che, J Xu, S Su, X Sun, M Li, Y Zhang - The Chinese-German Journal of …, 2013 - Springer
Abstract Objective Recombinant human Endostatin (rh-Endostatin, YH-16) can reverse
cisplatin resistance in A549/DDP cells. However, the possible effect of rh-Endostatin in …

Results of phase III trial of rh-endostatin (YH-16) in advanced non-small cell lung cancer (NSCLC) patients

Y Sun, J Wang, Y Liu, X Song, Y Zhang, K Li… - Journal of Clinical …, 2005 - ascopubs.org
7138 Background: Endostar (rh-endostatin, YH-16) is a new recombinant human endostatin
developed by Medgenn Co. Ltd. Pre-clinical study indicates that it can inhibit tumor …