The tumor microenvironment is an ecosystem composed of multiple types of cells, such as
tumor cells, immune cells, and cancer-associated fibroblasts. Cancer cells grow faster than …

Tumor microenvironment (TME) is composed of tumor cells, immune cells, cytokines,
extracellular matrix, etc. The immune system and the metabolisms of glucose, lipids, amino …

At the centre of the therapeutic dilemma posed by cancer is the question of how to develop
more effective treatments that discriminate between normal and cancerous tissues. Decades …

Advances in immunotherapy have underscored the importance of antitumor immune
responses in controlling cancer. However, the tumor microenvironment (TME) imposes …

Simple Summary One of the causes of failure of anticancer therapies is the reprogramming
of lipid metabolism. Cells of innate and adaptive immunity present in the tumor …

Immune cells survey and patrol throughout the body and sometimes take residence in niche
environments with distinct cellular subtypes and nutrients that may fluctuate from those in …

The scientific knowledge about tumor metabolism has grown at a fascinating rate in recent
decades. We now know that tumors are highly active both in their metabolism of available …

Cancer progression generates a chronic inflammatory state that dramatically influences
hematopoiesis, originating different subsets of immune cells that can exert pro-or anti-tumor …

Nutrients are essential for supporting tumor growth and immune cell function in the tumor
microenvironment, but emerging evidence reveals a paradoxical competition and …

Cancer is a complex succession of disease progressively associated with uncontrolled
growth and capability of cells eluding the body's natural mechanism of defense and cell …