Objective: To assess the response rate of patients with rectal adenocarcinoma to
neoadjuvant therapy and to identify the predictors of histological regression after …

Background Patients who have a good clinical and/or pathologic response to neoadjuvant
chemoradiotherapy (nCRT) for rectal cancer have better long‐term outcomes and can …

Purpose/objectives Induction chemotherapy followed by chemoradiation and surgical
resection in rectal cancer, known as total neoadjuvant therapy (TNT), is associated with …

Background Neoadjuvant chemoradiation therapy (CRT) is an important management
strategy in rectal carcinoma. Different systems grading response have shown varying …

Following standard neoadjuvant chemoradiotherapy and total mesorectal excision, some
patients with locally advanced rectal cancer achieve good response (pathological T0–2N0) …

Purpose Standard of care for locally advanced rectal cancer is neoadjuvant
chemoradiotherapy followed by surgery. This study identified predictive factors for tumour …

Background For locally advanced rectal cancer, response to neoadjuvant radiation has
been associated with improved outcomes but has not been well characterized in general …

Results Eighty-six percent of patients had locally advanced disease (cT3-4 and/or cN+). The
majority (68%) of patients received conventional preoperative chemoradiation, though some …

BACKGROUND: The benefit of adjuvant therapy is unclear in patients with rectal cancer
achieving a pathologic complete response after neoadjuvant chemoradiotherapy and total …

Objective: This study evaluates factors associated with a pathologic complete response
(pCR) after neoadjuvant chemoradiation for rectal cancer. Summary Background Data …