Objective To examine the effect of pSer9-GSK-3β on breast cancer and to determine
whether the underlying metabolic and immunological mechanism is associated with …

Abstract Background Aberrant expression of Aldo-Keto reductase family 1 member B10
(AKR1B10) was associated with tumor size and metastasis of breast cancer in our published …

The PI3K/Akt/mTORC1 pathway plays prominent roles in malignant transformation,
prevention of apoptosis, drug resistance, and metastasis. One molecule regulated by this …

Background Phosphorylated AKT is highly expressed or overexpressed in chemoresistant
tumor samples. However, the precise molecular mechanism involved in AKT …

Background/Aims: Glycolysis, a multi-step enzymatic reaction, is considered to be the root of
cancer development and progression. The aim of this study is to figure out which glycolysis …

Background/Aims: Next-generation sequencing (NGS) has revealed abundant long
noncoding RNAs (lncRNAs) that have been characterized as critical components of cancer …

Potassium ion channels are emerging as promalignant factors involved in cancer
progression. In this study, we found that invading human gastric cancer cells express high …

Background Numerous molecules have been introduced to participate in the formation of
breast cancer, the most common malignancy in women. Among them, neuropeptide …

Phosphoglycerate kinase 1 (PGK1), a critical component of the glycolytic pathway, relates to
the development of various cancers. However, the mechanisms of PGK1 inhibition and …

IKBKE, a non-canonical inflammatory kinase, is frequently amplified or activated, and plays
predominantly oncogenic roles in human cancers, especially in breast cancer. However, the …