[HTML][HTML] Diagnostic value of 5 serum biomarkers for hepatocellular carcinoma with different epidemiological backgrounds: A large-scale, retrospective study

D Liu, Y Luo, L Chen, L Chen, D Zuo, Y Li… - Cancer biology & …, 2021 - ncbi.nlm.nih.gov
Objective: Hepatocellular carcinoma (HCC) is a lethal global disease that requires an
accurate diagnosis. We assessed the potential of 5 serum biomarkers (AFP, AFU, GGT-II …

Direct comparison of five serum biomarkers in early diagnosis of hepatocellular carcinoma

H Chen, Y Zhang, S Li, N Li, Y Chen… - Cancer management …, 2018 - Taylor & Francis
Background Although a number of serum biomarkers for detection of hepatocellular
carcinoma (HCC) have been explored, their exact diagnostic value remains unclear. We …

Serological tumor markers of hepatocellular carcinoma: a meta-analysis

TD Hussein - The International journal of biological markers, 2015 - journals.sagepub.com
Background The clinical value of serum α-fetoprotein (AFP) to detect hepatocellular
carcinoma (HCC) has been questioned due to its low sensitivity and specificity. Other than …

[PDF][PDF] Longitudinal assessment of three serum biomarkers to detect very early‐stage hepatocellular carcinoma

J Choi, GA Kim, S Han, W Lee, S Chun, YS Lim - Hepatology, 2019 - Wiley Online Library
We aimed to determine the surveillance performance of alpha‐fetoprotein (AFP), lectin‐
reactive AFP (AFP‐L3), des‐gamma‐carboxy prothrombin (DCP), and their combinations for …

Risk factors for hepatocellular carcinoma may impair the performance of biomarkers: a comparison of AFP, DCP, and AFP-L3

ML Volk, JC Hernandez, GL Su, AS Lok… - Cancer …, 2007 - content.iospress.com
Current surveillance strategies for hepatocellular carcinoma (HCC) are applied uniformly in
patients with cirrhosis, regardless of their cancer risk. The aim of this study was to compare …

[HTML][HTML] Evaluation of individual and combined applications of serum biomarkers for diagnosis of hepatocellular carcinoma: a meta-analysis

B Hu, X Tian, J Sun, X Meng - International journal of molecular sciences, 2013 - mdpi.com
The clinical value of Serum alpha-fetoprotein (AFP) to detect early hepatocellular carcinoma
(HCC) has been questioned due to its low sensitivity and specificity found in recent years …

Clinical validation of combined serological biomarkers for improved hepatocellular carcinoma diagnosis in 961 patients

G Giannelli, E Fransvea, P Trerotoli, M Beaugrand… - Clinica Chimica …, 2007 - Elsevier
BACKGROUND: Alpha-fetoprotein (AFP), the only serological marker currently available for
the detection of hepatocellular carcinoma (HCC), is unsatisfactory because of its poor …

[HTML][HTML] Recently introduced biomarkers for screening of hepatocellular carcinoma: a systematic review and meta-analysis

CDM Witjes, SM van Aalten, EW Steyerberg… - Hepatology …, 2013 - Springer
Purpose Early detection of hepatocellular carcinoma (HCC) is essential for improved
prognosis and long-term survival. To date, screening for HCC depends on serological …

Dynamic changes in serum markers and their utility in the early diagnosis of all stages of hepatitis B-associated hepatocellular carcinoma

M Wu, Z Liu, X Li, A Zhang, N Li - OncoTargets and therapy, 2020 - Taylor & Francis
Objective This study aimed to evaluate the individual and combined diagnostic values of
serum alpha-fetoprotein (AFP), des-gamma-carboxyprothrombin (DCP), glypican-3 (GPC3) …

[HTML][HTML] Evaluation of the combined application of AFP, AFP-L3%, and DCP for hepatocellular carcinoma diagnosis: a meta-analysis

X Wang, Y Zhang, N Yang, H He, X Tao… - BioMed research …, 2020 - hindawi.com
The role of α-fetoprotein (AFP) in the surveillance and diagnosis of hepatocellular carcinoma
(HCC) has been questioned in recent years due to its low sensitivity and specificity. In …