Objective To explore whether overexpression of human telomerase reverse transcriptase
(hTERT) in Raji cells can protect against etoposide (VP-16)-induced apoptosis. Methods A …

Aim To explore the regulation of telomerase activity in camptothecin induced apoptosis of
human leukemia HL-60 cells. Methods Apoptosis of HL-60 cells was induced by …

AIM: To explore the effects of the combined use of human telomerase reverse transcriptase
(hTERT) gene antisense oligodeoxynucleotide (ASODN) and cisplatin on apoptosis of HL …

AIM: To explore the regulation of telomerase activity in camptothecin induced apoptosis of
human leukemia HL-60 cells. METHODS: Apoptosis of HL-60 cells was induced by …

Objective To investigate telomerase activity of MCF-7 mammary cancer cells during
apoptosis induced by sodium butyrate (SB) in vitro and its mechanism. Methods The …

Background Human telomerase reverse transcriptase (hTERT) is a catalytic enzyme that is
required for telomerase activity (TA) and cancer progression. Telomerase inhibition or …

Objective To explore the inhibitory effects of gene expression and functional activity of
telomerase in leukemia cell lines by in vitro antisense hTERT treatment. Methods An …

Background Telomerase activity is found in 85%-90% of all human cancers but not in their
adjacent normal cells. Human telomerase reverse transcriptase (hTERT) is an essential …

Human telomerase reverse transcriptase (hTERT) plays an important role in the
development of tumors and has been investigated as a potent target for anticancer therapy …

Aim: To investigate the effect of inhibition of telomerase with human telomerase reverse
transcriptase (hTERT) antisense on tumor necrosis factor‐α (TNF‐α)‐induced apoptosis in …