[HTML][HTML] A novel expressed prostatic secretion (EPS)-urine metabolomic signature for the diagnosis of clinically significant prostate cancer

D Drago, A Andolfo, E Mosca, A Orro… - Cancer biology & …, 2021 - ncbi.nlm.nih.gov
Objective: Significant efforts are currently being made to identify novel biomarkers for the
diagnosis and risk stratification of prostate cancer (PCa). Metabolomics can be a very useful …

[HTML][HTML] Non-invasive urinary metabolomic profiling discriminates prostate cancer from benign prostatic hyperplasia

C Pérez-Rambla, L Puchades-Carrasco… - Metabolomics, 2017 - Springer
Abstract Introduction Prostate cancer (PCa) is one of the most common malignancies in men
worldwide. Serum prostate specific antigen (PSA) level has been extensively used as a …

[HTML][HTML] Prediction of clinically significant prostate cancer through urine metabolomic signatures: A large-scale validated study

HP Huang, CH Chen, KH Chang, MS Lee… - Journal of Translational …, 2023 - Springer
Purpose Currently, there are no accurate markers for predicting potentially lethal prostate
cancer (PC) before biopsy. This study aimed to develop urine tests to predict clinically …

[HTML][HTML] 1H-NMR-based urine metabolomics of prostate cancer and benign prostatic hyperplasia

M Zniber, T Lamminen, P Taimen, PJ Boström… - Heliyon, 2024 - cell.com
Abstract Background Prostate cancer (PCa) and benign prostatic hyperplasia (BPH) are
prevalent conditions affecting a significant portion of the male population, particularly with …

Metabolomics-derived prostate cancer biomarkers: fact or fiction?

D Kumar, A Gupta, A Mandhani… - Journal of proteome …, 2015 - ACS Publications
Despite continuing research for precise probing and grading of prostate cancer (PC)
biomarkers, the indexes lack sensitivity and specificity. To search for PC biomarkers, we …

[HTML][HTML] Metabolomic profiles of intact tissues reflect clinically relevant prostate cancer subtypes

I Dudka, K Lundquist, P Wikström, A Bergh… - Journal of Translational …, 2023 - Springer
Background Prostate cancer (PC) is a heterogenous multifocal disease ranging from
indolent to lethal states. For improved treatment-stratification, reliable approaches are …

Identification of the metabolic signatures of prostate cancer by mass spectrometry‐based plasma and urine metabolomics analysis

C Yu, L Niu, L Li, T Li, L Duan, Z He, Y Zhao… - The …, 2021 - Wiley Online Library
Abstract Objective Prostate cancer (PCa) is one of the most commonly diagnosed cancers
among men which is associated with profound metabolic changes. Systematic analysis of …

Application of metabolomics to prostate cancer

BJ Trock - Urologic Oncology: Seminars and Original …, 2011 - Elsevier
The prostate has long been known to exhibit unique metabolite profiles. In the last decade,
advances in nuclear magnetic resonance spectroscopy and mass spectrometry have been …

[HTML][HTML] Metabolic markers in blood can separate prostate cancer from benign prostatic hyperplasia

GF Giskeødegård, AF Hansen, H Bertilsson… - British journal of …, 2015 - nature.com
Background: An individualised risk-stratified screening for prostate cancer (PCa) would
select the patients who will benefit from further investigations as well as therapy. Current …

[HTML][HTML] Metabolomics profiling discriminates prostate cancer from benign prostatic hyperplasia within the prostate-specific antigen gray zone

B Xu, Y Chen, X Chen, L Gan, Y Zhang, J Feng… - Frontiers in …, 2021 - frontiersin.org
Objective: Prostate cancer (PCa) is the second most common male malignancy globally.
Prostate-specific antigen (PSA) is an important biomarker for PCa diagnosis. However, it is …