Objective The aim of this study was to investigate mRNA expression of tyrosine-kinase
receptors (TRKs) and neurotrophins (NTs) in human neuroblastomas. Methods Expression …

Expression of trk family genes are prognostic indicators of neuroblastoma. However, the
functional role of neurotrophins and their receptors in neuroblastomas in vivo is still unclear …

The clinical hallmark of neuroblastoma is heterogeneity. Biologically, ploidy and N-Myc
amplification are currently the only 2 features used to define risk group and to determine …

There is considerable interest in the role of the TRK family of neurotrophin receptors in
regulating the survival, growth and differentiation of normal and neoplastic nerve cells …

To study tyrosine-kinase receptor expression in human neuroblastomas. Methods The
expression levels of TrkA, TrkB and TrkC receptors were semiquantitatively examined by …

Human neuroblastomas express the neurotrophin receptors trk-A and trk-B. Favourable
outcome is associated with expression of trk-A, while unfavourable, MYCN amplified …

Objective: To study the correlativity and clinical significance of gene expression of tyrosine-
kinase receptors (TrkA, TrkB) and vascular endothelial growth factor (VEGF) in human …

Expression of different neurotrophin receptors of the tyrosine kinase (Trk) family plays an
important role in the biology and clinical behavior of neuroblastomas (NB). Observations …

Little is known about the signal transduction pathways of TRK family receptors in
neuroblastoma (NB) cells. In this study, an NB cell line, designated MP‐N‐TS, was …

Objective To study the correlation and clinical significance of expression of tyrosine-kinase
receptors (TrkA and TrkB) and vascular endothelial growth factor (VEGF) in human …