Objective To study the mechanism of IFN on CML. Methods Samples of 15 CML patients and
10 healthy controls were studied. The flow cytometry was performed to identify circulating …

It is currently established that the immune system plays a critical role in the control of chronic
myelogenous leukemia (CML). Several cell populations including T cells, dendritic cells …

Chronic myelogenous leukemia (CML) is a malignant myeloproliferative disease arising
from the clonal expansion of a stem cell with the typical Philadelphia (Ph) chromosome …

The purpose of this study was to investigate the mechanism of effects of interferon-alpha
(IFN-alpha) on chronic myeloid leukemia (CML). Bone marrow mononuclear cells (BMMNC) …

The ability of interferon-α (IFN-α) to induce dendritic cell (DC) differentiation in chronic
myeloid leukemia (CML) was evaluated. Peripheral blood mononuclear cells from CML …

Adoptive immunotherapy in form of donor leukocyte infusions is effective in a significant
number of patients with chronic myeloid leukemia (CML) that have relapsed after allogeneic …

Objective: To explore the effects of interferon (IFN)-α on the phenotype and function of
dendritic cells (DCs) derived from acute myeloid leukaemia (AML) cells in vitro. Methods …

It is currently established that the immune system plays a critical role in the control of chronic
myelogenous leukemia (CML). Several cell populations including T cells, dendritic cells (Dc) …

Chronic myelogenous leukemia (CML) is a malignant myeloproliferative disease arising
from the clonal expansion of a stem cell expressing the bcr/abl oncogene. CML patients …

Plasmacytoid dendritic cells (PDCs) are crucial effectors in innate immunity. In this study, we
show that imatinib, a potent inhibitor of BCR/ABL tyrosine kinase activity, in the presence of …