Objective To observe the pattern of changes in the proliferation and apoptosis at different
stages of large bowel carcinoma in mice, and to explore the effects of the imbalance of …

Objective To investigate action of apoptosis in tumorigenesis by observation of the
relationship between apoptosis and proliferation. Method Using terminal deoxynucleotidyl …

Objective To investigate the effects of apoptosis and its regulating genes in different stages
of malignant transformation of large intestine epithelium in colorectal adenoma and …

Epithelial homeostasis in colorectal tumorigenesis is dependent not only on the rate of cell
production but also on the rate of apoptosis, a genetically programmed process of …

Objective To assess apoptotic status during the development of colorectal cancer and its
prognostic value. Methods The apoptotic frequency of 168 fresh adenocarcinoma …

To investigate the growth and progression of colorectal cancer, cell production versus cell
loss in colorectal cancer was examined using the proliferating cell nuclear antigen (PCNA) …

Ki-67-positive cells in the upper half area than in the lower half area, while the depressed
lesions had more proliferating cells in the lower half area. Onthe other hand, TUNEL …

To study the early alterations in carcinogenesis, we determined apoptosis and proliferation
in rat mucin depleted foci (MDF), precancerous lesions in the colon under basal conditions …

BACKGROUND Apoptotic cell death plays an important role in the proliferation and turnover
of cells in various tumors. The relationship between apoptosis and cell proliferation was …

To evaluate the relationship between cell proliferation and apoptosis in sporadic colorectal
carcinogenesis, immunohistochemistry for proliferation-associated antigen Ki-67 and in situ …