Significance: The detrimental effects of ionizing radiation (IR) involve a highly orchestrated
series of events that are amplified by endogenous signaling and culminating in oxidative …

The endothelium, a tissue that forms a single layer of cells lining various organs and cavities
of the body, especially the heart and blood as well as lymphatic vessels, plays a complex …

Abstract Treatment-related side effects are a major clinical problem in cancer treatment.
They lead to reduced compliance to therapy as well as increased morbidity and mortality …

Radiation-induced heart disease (RIHD) is a potential late side-effect of thoracic
radiotherapy resulting in left ventricular hypertrophy (LVH) and fibrosis due to a complex …

The long-term survival rate of cancer patients has been increasing as a result of advances in
treatments and precise medical management. The evidence has accumulated that the …

Hypertension is one of the most prevalent diseases in cardiology. The angiotensin receptor
blockers (ARBs)/angiotensin converting enzyme inhibitors (ACEIs) are widely used drugs to …

Radiation-induced lung injury (RILI) is one of the most common complications associated
with radiotherapy, characterized by early-stage radiation pneumonia and subsequent …

Aim This work aims to explore the role of diminazene aceturate (DIZE) in the enhancement
of angiotensin-converting enzyme-2 (ACE2) to prevent the inflammatory and fibrotic …

The objective of this work was to evaluate the effect of a bradykinin‐potentiating factor (BPF)
isolated from Leiurus quinquestriatus scorpion venom as a natural modulator of radiation …

Acute pancreatitis (AP) usually causes acute lung injury, which is also known as acute
pancreatitis associated lung injury (APALI). This study aimed to investigate whether captopril …