Light sources and dosimetry techniques for photodynamic therapy

MM Kim, A Darafsheh - Photochemistry and photobiology, 2020 - Wiley Online Library
Effective treatment delivery in photodynamic therapy (PDT) requires coordination of the light
source, the photosensitizer, and the delivery device appropriate to the target tissue. Lasers …

Clinical therapies and nano drug delivery systems for urinary bladder cancer

P Jain, H Kathuria, M Momin - Pharmacology & Therapeutics, 2021 - Elsevier
Bladder cancer is the 10 th most commonly occurring malignancy worldwide with a 75% of 5-
year survival rate, while it ranks 13 th among the deaths occurring due to cancer. The …

Photodynamic therapy: Inception to application in breast cancer

SM Banerjee, AJ MacRobert, CA Mosse, B Periera… - The Breast, 2017 - Elsevier
Photodynamic therapy (PDT) is already being used in the treatment of many cancers. This
review examines its components and the new developments in our understanding of its …

[HTML][HTML] Nanotechnology in modern photodynamic therapy of cancer: A review of cellular resistance patterns affecting the therapeutic response

EP Chizenga, H Abrahamse - Pharmaceutics, 2020 - mdpi.com
Photodynamic therapy (PDT) has emerged as a potential therapeutic option for most
localized cancers. Its high measure of specificity and minimal risk of side effects compared to …

Current advances in photoactive agents for cancer imaging and therapy

D Broadwater, HCD Medeiros, RR Lunt… - Annual review of …, 2021 - annualreviews.org
Photoactive agents are promising complements for both early diagnosis and targeted
treatment of cancer. The dual combination of diagnostics and therapeutics is known as …

pH-activatable singlet oxygen-generating boron-dipyrromethenes (BODIPYs) for photodynamic therapy and bioimaging

S Radunz, S Wedepohl, M Röhr… - Journal of Medicinal …, 2020 - ACS Publications
Singlet oxygen can severely damage biological tissue, which is exploited in photodynamic
therapy (PDT). In PDT, the effective range is limited by the distribution of the photosensitizer …

Halogen-containing BODIPY derivatives for photodynamic therapy

M Gorbe, AM Costero, F Sancenon… - Dyes and …, 2019 - Elsevier
Abstract Two iodinated (1 and 2) and two brominated (3 and 4) BODIPY-based
photosensitizers are prepared and characterized using slightly modified synthetic …

[HTML][HTML] Phthalocyanine and its formulations: a promising photosensitizer for cervical cancer phototherapy

LR Carobeli, LEF Meirelles, GMZF Damke, E Damke… - Pharmaceutics, 2021 - mdpi.com
Cervical cancer is one of the most common causes of cancer-related deaths in women
worldwide. Despite advances in current therapies, women with advanced or recurrent …

Thermosensitive nanocomposite gel for intra-tumoral two-photon photodynamic therapy

L Luo, Q Zhang, Y Luo, Z He, X Tian… - Journal of controlled …, 2019 - Elsevier
We propose here a new approach to achieve intratumoral near-infrared (NIR) two-photon
photodynamic therapy (PDT). We established a composite micellar thermosensitive …

[HTML][HTML] Characterization of plasma-derived protoporphyrin-IX-positive extracellular vesicles following 5-ALA use in patients with malignant glioma

PS Jones, A Yekula, E Lansbury, JL Small, C Ayinon… - …, 2019 - thelancet.com
Background Malignant gliomas are rapidly progressive brain tumors with high mortality.
Fluorescence guided surgery (FGS) with 5-aminolevulinic acid (5-ALA) provides fluorescent …