[HTML][HTML] Development of Glycosylation-Modified DPPA-1 Compounds as Innovative PD-1/PD-L1 Blockers: Design, Synthesis, and Biological Evaluation

P Deng, X Dong, Z Wu, X Hou, L Mao, J Guo, W Zhao… - Molecules, 2024 - mdpi.com
In the context of peptide drug development, glycosylation plays a pivotal role. Accordingly, L-
type peptides were synthesized predicated upon the PD-1/PD-L1 blocker DPPA-1 …

Cost-Effective Synthesis, Stability-Guided Structural Optimization and Anticancer Evaluation of First-in-Class Oncolytic Peptide Ltx-315

M Song, Q Liu, JF Yao, YT Wang, YN Ma, H Xu… - Available at SSRN … - papers.ssrn.com
Oncolytic peptides represented potential novel candidates for anticancer treatments
especially drug-resistant cancer cell lines. One of the most promising and extensively …