In recent years, oncolytic viruses have emerged as promising agents for treating various
cancers. An oncolytic virus is a non-pathogenic virus that, due to genetic manipulation, tends …

Glioblastoma is one of the most malignant and aggressive tumors of the central nervous
system. Despite the standard therapy consisting of maximal surgical resection and chemo …

Background An insufficient number of intratumoral CD8+ T lymphocytes is a major barrier to
antitumor immunity and immunotherapy. High endothelial venules (HEVs) are the major …

Immunotherapy represents a promising strategy for cancer treatment that utilizes immune
cells or drugs to activate the patient's own immune system and eliminate cancer cells. One of …

Glioma is a common primary central nervous system malignant tumor in clinical, traditional
methods such as surgery and chemoradiotherapy are not effective in treatment. Therefore …

Recent advances in cancer immunotherapy harness the immune system to precisely target
cancer. These include the use of immunosuppressive agents, NK cell recovery, changes in …

Oncolytic viruses (OVs) are attenuated viruses that have been engineered to selectively
infect and kill cancer cells. OVs exert anti-tumour effects through different mechanisms that …