[HTML][HTML] Circadian disruption and mental health: the chronotherapeutic potential of microbiome-based and dietary strategies

P Codoñer-Franch, M Gombert… - International Journal of …, 2023 - mdpi.com
Mental illness is alarmingly on the rise, and circadian disruptions linked to a modern lifestyle
may largely explain this trend. Impaired circadian rhythms are associated with mental …

[HTML][HTML] The impact of aging and oxidative stress in metabolic and nervous system disorders: programmed cell death and molecular signal transduction crosstalk

K Maiese - Frontiers in Immunology, 2023 - frontiersin.org
Life expectancy is increasing throughout the world and coincides with a rise in non-
communicable diseases (NCDs), especially for metabolic disease that includes diabetes …

[HTML][HTML] The metabolic basis for nervous system dysfunction in alzheimer's disease, parkinson's disease, and huntington's disease

K Maiese - Current neurovascular research, 2023 - ncbi.nlm.nih.gov
Disorders of metabolism affect multiple systems throughout the body, but may have the
greatest impact on both central and peripheral nervous systems. Current available …

[HTML][HTML] Innovative therapeutic strategies for cardiovascular disease

K Maiese - EXCLI journal, 2023 - ncbi.nlm.nih.gov
As a significant non-communicable disease, cardiovascular disease is the leading cause of
death for both men and women, comprises almost twenty percent of deaths in most racial …

[HTML][HTML] Molecular mechanisms of tumour development in glioblastoma: an emerging role for the circadian clock

N Nelson, A Relógio - NPJ Precision Oncology, 2024 - nature.com
Glioblastoma is one of the most lethal cancers with current therapeutic options lacking major
successes. This underlines the necessity to understand glioblastoma biology on other levels …

Circadian rhythm of voided volume, maximum flow rate, and voiding time evaluated by toilet uroflowmetry in hospitalized women with nocturia

A Yoshiyama, A Tsujimura, I Hiramatsu, J Morino… - Urology, 2023 - Elsevier
Objective To clarify the circadian rhythm of urination in hospitalized women with nocturia
measured by toilet uroflowmetry and its age-related change. Methods We evaluated 2602 …

[HTML][HTML] Circadian disruption does not alter tumorigenesis in a mouse model of lymphoma

RM Mello, M Pariollaud, KA Lamia - F1000Research, 2023 - ncbi.nlm.nih.gov
Background: Disruption of natural light cycles, as experienced by shift workers, is linked to
enhanced cancer incidence. Several mouse models of cancer develop more severe disease …

[HTML][HTML] Period2 is associated with immune cell infiltration and is a potential diagnostic and prognostic marker for hepatocellular carcinoma

X Chen, Q Zhao, H Wang, K Qiu, X Deng… - Frontiers in Molecular …, 2023 - frontiersin.org
Background: Hepatocellular carcinoma (HCC) health challenge worldwide. Many studies
showed that circadian rhythms play a critical role in tumor development. This study aimed to …

The role of circadian clock in regulating cell functions: implications for diseases

Y Lin, L He, Y Cai, X Wang, S Wang, F Li - MedComm, 2024 - Wiley Online Library
The circadian clock system orchestrates daily behavioral and physiological rhythms,
facilitating adaptation to environmental and internal oscillations. Disruptions in circadian …

[HTML][HTML] Early Detection of Disease Progression in Metastatic Cancers: Could CTCs Improve RECIST Criteria?

V Magri, L Marino, G De Renzi, M De Meo, F Salvatori… - Biomedicines, 2024 - mdpi.com
Early detection of disease progression is a crucial issue in the management of cancer
patients, especially in metastatic settings. Currently, treatment selection mostly relies on …