Non‐small cell lung cancer in China

P Chen, Y Liu, Y Wen, C Zhou - Cancer Communications, 2022 - Wiley Online Library
In China, lung cancer is a primary cancer type with high incidence and mortality. Risk factors
for lung cancer include tobacco use, family history, radiation exposure, and the presence of …

Clinical Benefit, Price, and Uptake for Cancer Biosimilars vs Reference Drugs in China: A Systematic Review and Meta-Analysis

X Luo, X Du, Z Li, J Liu, X Lv, H Li, Q Guo… - JAMA Network …, 2023 - jamanetwork.com
Importance The high cost of biologics used to treat cancer has been an increasing burden in
the world. In China, the recent approval of cancer biosimilar drugs to resolve this problem is …

Polymeric micellar paclitaxel (Pm-Pac) prolonged overall survival for NSCLC patients without pleural metastasis

J Lu, A Gu, W Wang, A Huang, B Han… - International Journal of …, 2022 - Elsevier
Nanoparticle polymeric micellar paclitaxel (Pm-Pac) has been demonstrated to have a
safety profile and efficacy in advanced non-small cell lung cancer (NSCLC) patients …

Paclitaxel has a reduced toxicity profile in healthy rats after polymeric micellar nanoparticle delivery

J Lu, Y Lou, Y Zhang, R Zhong, W Zhang… - International Journal …, 2023 - Taylor & Francis
Background Nanocarrier platforms have been indicated to have great potential in clinical
practice to treat non-small cell lung cancer (NSCLC). Our previous Phase III clinical study …

[HTML][HTML] Efficacy and safety of bevacizumab biosimilar compared with reference bevacizumab in locally advanced and advanced non-small cell lung cancer patients: A …

Z Zhao, L Zhao, G Xia, J Lu, B Shen, G Zhou… - Frontiers in …, 2023 - frontiersin.org
Background Bevacizumab has played an important role in the systemic treatment of patients
with advanced non-small-cell lung cancer (NSCLC) without gene mutation. In recent years …

Efficacy and safety of adding bevacizumab biosimilar or original drug to platinum-based chemotherapy as first-line treatment in patients with advanced NSCLC: a …

L Yang, M Liu, X Cao, N Li, B Zheng… - … Advances in Medical …, 2022 - journals.sagepub.com
Introduction: The role of bevacizumab combined with paclitaxel and carboplatin in the first-
line treatment of advanced non-squamous non-small-cell lung cancer (NSCLC) has been …

[HTML][HTML] ctDNA-Profiling-Based UBL Biological Process Mutation Status as a Predictor of Atezolizumab Response Among TP53-Negative NSCLC Patients

J Lu, Y Zhang, Y Lou, B Yan, B Zou, M Hu… - Frontiers in …, 2021 - frontiersin.org
Atezolizumab, an immune checkpoint inhibitor, has been approved for use in clinical
practice in non-small cell lung cancer (NSCLC) patients, but potential biomarkers for …

[HTML][HTML] TP53 Mutation Status and Biopsy Lesion Type Determine the Immunotherapeutic Stratification in Non-Small-Cell Lung Cancer

J Lu, R Zhong, Y Lou, M Hu, Z Yang, Y Wang… - Frontiers in …, 2021 - frontiersin.org
Immunotherapy, a chemotherapy-free process, has emerged as a promising therapeutic
strategy to prolong the overall survival (OS) of patients with non-small-cell lung cancer …

Biosimilar monoclonal antibodies in China: A patent review

JW Liu, YH Yang, N Wu, JF Wei - Bioengineered, 2022 - Taylor & Francis
Biosimilars play an important role in reducing the burden on patients and increasing the
market competition. Biosimilar monoclonal antibodies are currently one of the hotspots of …

[HTML][HTML] Equivalent efficacy assessment of QL1101 and bevacizumab in nonsquamous non-small cell lung cancer patients: a two-year follow-up data update

J Lu, T Chu, H Liu, M Hu, Y Lou, Y Zhang… - Chinese Journal of …, 2022 - ncbi.nlm.nih.gov
Objective Anti-vascular endothelial growth factor (VEGF) monoclonal antibodies are an
effective means of treating non-small cell lung cancer (NSCLC). Here, we aim to update the …