Proteogenomic analyses of hepatocellular carcinomas (HCC) have focused on early-stage,
HBV-associated HCCs. Here we present an integrated proteogenomic analysis of HCCs …

RIO (right open reading frame) family of kinases including RIOK1, RIOK2 and RIOK3 are
known for their role in the ribosomal biogenesis. Dysfunction of RIO kinases have been …

The standard regimen treatment has improved GBM outcomes, but the survival rate of
patients is still unsatisfactory. Temozolomide (TMZ) resistance is one of main reasons …

Colorectal cancer (CRC) is the third most common cause of cancer-related deaths. The five-
year relative survival rate for CRC is estimated to be approximately 90% for patients …

Background Previous studies have suggested an important role for N6-methyladenosine
(m6A) modification in the proliferation of glioma cells. N6, 2′-O-dimethyladenosine (m6Am) …

Angiogenesis contributes to the progression of several diseases including cancer or age-
related macular degeneration and is crucially driven by pathologically hyperactive …

Background. Glioma is the most common primary intracranial tumor in adult patients. Among
them, glioblastoma is a highly malignant one with a poor prognosis. Flavonoids are a class …

Aerobic glycolysis is the primary energy supply mode for glioblastoma (GBM) cells to
maintain growth and proliferation. However, due to the metabolic reprogramming of tumor …

Background Colorectal cancer (CRC) is the third most common of cancer-related deaths.
Nucleolar protein 14 (NOP14) is known to play different roles in diverse types of cancers …

The metabolism of tumor cells is characterized by the regulation of demand, nutrient supply
and metabolic enzymes, which are different in cancer tissues from those in corresponding …