MicroRNAs (miRNAs) are evolutionarily conserved small non-coding RNAs, that are
involved in the multistep process of carcinogenesis, contributing to all established hallmarks …

Simple Summary Canine malignant lymphoma is one of the most common neoplasias in
dogs. Even though breed influences the prevalence and prognosis, most cases present …

Cutaneous 5T cell lymphoma (CTCL), characterized by malignant T cells infiltrating the skin
with potential for dissemination, remains a challenging disease to diagnose and treat due to …

Epigenetic dysregulation is a key factor leading to oncogenesis and tumor progression 1. To
date, seven agents in three epigenetic target classes have been approved by the US Food …

Abstract Prostaglandin D2 (PGD2), an arachidonic acid metabolite, has been implicated in
allergic responses, parasitic infection and tumor development. The biological functions and …

Introduction Cutaneous T cell lymphoma (CTCL) is a rare and incurable group of non-
Hodgkin lymphomas that manifest as patches, plaques, tumors, and/or erythroderma in the …

Sézary syndrome (SS) is a rare and aggressive type of cutaneous T cell lymphoma (CTCL)
with a poor prognosis. Intra-tumoral heterogeneity caused by different disease …

Cutaneous T-cell lymphoma (CTCL) is a type of cancer that affects skin, and is characterized
by abnormal T-cells in the skin. Epigenetic changes have been found to play a significant …

Cutaneous T-cell lymphomas (CTCLs) are a subset of T-cell malignancies presenting in the
skin. The treatment options for CTCL, in particular in advanced stages, are limited. One of …

Epigenetics encompasses heritable, reversible gene expression patterns that do not arise
from mutations in genomic DNA but, rather, are regulated by DNA methylation, histone …