The low efficiency of currently-used anti-cancer therapies poses a serious challenge,
especially in the case of malignant melanoma, a cancer characterized by elevated …

Background Cancer is a major burden of disease worldwide and increasing evidence shows
that inflammation contributes to cancer development and progression. Eicosanoids are …

COX-2, a key enzyme that catalyzed the rate-limiting steps in the conversion of arachidonic
acid to prostaglandins, played a pivotal role in the inflammatory process. Different from other …

The tumor microenvironment (TME) corresponds to a complex and dynamic interconnection
between the extracellular matrix and malignant cells and their surrounding stroma …

Aims Immune stress in broiler chickens is characterized by the development of persistent pro-
inflammatory responses that contribute to degradation of production performance. However …

Melanoma is one of the most severe cancerous diseases. The cells employ multiple
signaling pathways, such as ERK, HGF/c-MET, WNT, and COX-2 to cause the cell …

Curcumin is a polyphenolic substance extracted from plants such as Curcuma longa,
Curcuma zedoaria, and radix curcumae, and it has attracted much attention because of the …

Simple Summary Melanoma is a devastating skin cancer characterized by an impressive
metabolic plasticity. Melanoma cells are able to adapt to the tumor microenvironment by …

The correlation between chronic inflammation and cancer was initially identified in the 19th
century. Biomolecules like interleukins, chemokines, tumor necrosis factors, growth factors …

Cyano-phycocyanin is one of the active pigments of the blue-green algae and is usually
isolated from the filamentous cyanobacteria Arthrospira platensis Gomont (Spirulina). Due to …