Breast cancer liver metastasis: current and future treatment approaches

NS Rashid, JM Grible, CV Clevenger… - Clinical & experimental …, 2021 - Springer
Nearly all fatalities arising from breast tumors are attributable to distant metastases. Breast
cancer liver metastasis (BCLM) is associated with poor prognoses, with the median survival …

[HTML][HTML] Pancreatic cancer: challenges and opportunities in locoregional therapies

AY Bazeed, CM Day, S Garg - Cancers, 2022 - mdpi.com
Simple Summary Pancreatic cancer is a serious ongoing global health burden, with an
overall 5-year survival rate of less than 5%. One major hurdle in the treatment of this disease …

A single-center retrospective analysis of periprocedural variables affecting local tumor progression after radiofrequency ablation of colorectal cancer liver metastases

K Han, JH Kim, SG Yang, SH Park, HK Choi, SY Chun… - Radiology, 2021 - pubs.rsna.org
Background Local tumor progression (LTP) is associated with poorer survival in patients
undergoing radiofrequency ablation (RFA) for colorectal liver metastasis (CLM). An …

Incomplete radiofrequency ablation induced chemoresistance by up-regulating heat shock protein 70 in hepatocellular carcinoma

F Wang, C Xu, G Li, P Lv, J Gu - Experimental Cell Research, 2021 - Elsevier
Radiofrequency ablation (RFA) is a common minimally invasive treatment for hepatocellular
carcinoma (HCC). Incomplete RFA (iRFA) due to the sub-lethal heat shock challenge of …

[HTML][HTML] FRA-1: A key factor regulating signal transduction of tumor cells and a potential target molecule for tumor therapy

F Zeng, J He, X Jin, Q Liao, Z Chen, H Peng… - Biomedicine & …, 2022 - Elsevier
Abstract Fos-related antigen-1 (FRA-1) is a member of activator protein-1 (AP-1)
transcription factor superfamily, and FRA-1 is highly expressed in colon cancer, breast …

[HTML][HTML] Xanthohumol targets the ERK1/2‑Fra1 signaling axis to reduce cyclin D1 expression and inhibit non‑small cell lung cancer

F Gao, M Li, L Zhou, W Liu, H Zuo… - Oncology …, 2020 - spandidos-publications.com
High expression of cyclin D1 has a crucial role in the maintenance of unlimited cell growth in
human cancer cells. The present study indicated that cyclin D1 was overexpressed in …

Periprocedural risk factors for incomplete radiofrequency ablation of liver metastases from colorectal cancer: A single-center retrospective analysis

H Fan, X Wang, J Qu, W Lu, Z Pang… - International journal …, 2021 - Taylor & Francis
Objective To explore independent risk factors for incomplete radiofrequency ablation (iRFA)
of colorectal cancer liver metastases (CRLM) and evaluate adverse outcomes following …

Distinct effects of heat shock temperatures on mitotic progression by influencing the spindle assembly checkpoint

S Ota, Y Tanaka, R Yasutake, Y Ikeda, R Yuki… - Experimental Cell …, 2023 - Elsevier
Heat shock is a physiological and environmental stress that leads to the denaturation and
inactivation of cellular proteins and is used in hyperthermia cancer therapy. Previously, we …

[HTML][HTML] Comparison of percutaneous radiofrequency ablation for subcapsular and non-subcapsular colorectal cancer liver metastases

H Fan, X Wang, J Qu, W Lu, S Xu, X Wu, J Xia… - Frontiers in …, 2021 - frontiersin.org
Purpose: To evaluate the efficacy and safety of percutaneous radiofrequency ablation (RFA)
for subcapsular colorectal cancer liver metastases (CLMs). Materials and methods: With the …

[HTML][HTML] Specific inhibitor of matrix metalloproteinase decreases tumor invasiveness after radiofrequency ablation in liver tumor animal model

AN Jiang, JT Liu, K Zhao, H Wu, S Wang, K Yan… - Frontiers in …, 2020 - frontiersin.org
Objective To determine whether the specific inhibitor of matrix metalloproteinase (MMP)—
batimastat (BB-94)—could decrease the progression of liver tumor after radiofrequency …