The cell cycle is a collection of events by which cellular components such as genetic
materials and cytoplasmic components are accurately divided into two daughter cells. The …

Recently, there has been an increase in the incidence of malignant tumors among the older
population. Moreover, there is an association between aging and cancer. During the …

Bone metastasis is the main site of metastasis and causes the most deaths in patients with
prostate cancer (PCa). The mechanism of bone metastasis is complex and not fully clarified …

Due to poor T cell infiltration, tumors evade immune surveillance. Increased CD8+ T cell
infiltration in breast cancer suggests a satisfactory response to immunotherapy. COPS6 has …

BYSL, which encodes the human bystin protein, is a sensitive marker for astrocyte
proliferation during brain damage and inflammation. Previous studies have revealed that …

The COP9 signalosome (CSN) is a highly conserved protein complex composed of 8
subunits (CSN1 to CSN8). The individual subunits of the CSN play essential roles in cell …

The dysregulation of exosomal microRNAs (miRNAs) plays a crucial role in the development
and progression of cancer. This study investigated the role of a newly identified serum …

Endometrial cancer (EC) is a common malignant gynecological tumor arising from the
endometrium, with an annually increasing morbidity and mortality. The present study aimed …

The p16INK4A is a multifunction gene that includes regulation of the cell cycle, apoptosis,
senescence and tumor development. However, the effects of p16 in hydroquinone‐induced …

Hepatocellular carcinoma (HCC) is among the most common deadly tumors but still lacks
specific biomarkers for diagnosis, prognosis, and treatment guidance. The COP9 …