Simple Summary Melanoma is a form of skin cancer that has increased in incidence in the
last few decades. The main environmental risk factor is exposure to ultraviolet radiation …

Metastasis is the leading cause of melanoma-related mortality. Current therapies are rarely
curative for metastatic melanoma, revealing the urgent need to identify more effective …

Objective: Esophageal squamous cell carcinoma (ESCC) has high morbidity and mortality
rates worldwide. Cancer stem cells (CSCs) may cause tumor initiation, metastasis, and …

Several research reports delineated the significant role of miRNAs in cancer proliferation,
and their modulatory role in cancer mitigation, and drug resistance. Melanoma cells have …

Abnormal expression of the potassium channel tetramerization domain containing 12
(KCTD12) is closely related to the occurrence and development of various tumors, but a pan …

Cell migration is critical for several physiological and pathophysiological processes. It
depends on the coordinated action of kinases, phosphatases, Rho-GTPases proteins, and …

This study researched the function of long non‐coding RNA LINC00365 in lung
adenocarcinoma (LAD) progression. LINC00365, miR‐429, and KCTD12 expression in the …

Gamma-aminobutyric acid (GABA) is considered the primary inhibitory neurotransmitter in
the human cortex. However, whether GABA regulates melanogenesis has not been …

A core transcriptional regulatory circuit (CRC) is a group of interconnected auto-regulating
transcription factors (TFs) that form loops and can be identified by super-enhancers (SEs) …

Metastasis consists of sequential steps initiated by cancer cells invading from the primary
tumor site into neighboring tissues, followed by entry into the circulatory system and …