Because of their potent antitumor activity and their proinflammatory role, natural killer (NK)
cells are at the forefront of efforts to develop immuno-oncologic treatments. NK cells …

Reactive oxygen species (ROS) play a pivotal role in biological processes and continuous
ROS production in normal cells is controlled by the appropriate regulation between the silver …

Natural Killer (NK) cells are characterized by their potential to kill tumor cells by different
means without previous sensitization and have, therefore, become a valuable tool in cancer …

Metformin is the oldest and most commonly used first-line antidiabetic drug because of its
good clinical efficacy, high safety, low cost and easy access. At the same time, in recent …

Quality-of-life improvements have resulted in increasing attention being paid to research on
antiaging and antioxidation. Polyphenols are natural antioxidants with excellent biological …

Breast cancer rises as the most commonly diagnosed cancer in 2020. Among women,
breast cancer ranks first in both cancer incidence rate and mortality. Treatment resistance …

Driver mutations in oncogenic pathways, rewiring of cellular metabolism and altered ROS
homoeostasis are intimately connected hallmarks of cancer. Electrons derived from different …

Reactive oxygen species (ROS) play a dual role in the initiation, development, suppression,
and treatment of cancer. Excess ROS can induce nuclear DNA, leading to cancer initiation …

Radiotherapy (RT) is an effective treatment option for cancer patients, which induces the
production of reactive oxygen species (ROS) and causes oxidative stress (OS), leading to …

Exosomes are nanosized extracellular vesicles secreted by various cell types, including
those of the immune system, such as natural killer (NK) cells. They play a role in intercellular …