[HTML][HTML] Calcium permeable channels in cancer hallmarks

S Tajada, C Villalobos - Frontiers in pharmacology, 2020 - frontiersin.org
Cancer, the second cause of death worldwide, is characterized by several common criteria,
known as the “cancer hallmarks” such as unrestrained cell proliferation, cell death …

Role of the calcium toolkit in cancer stem cells

E Terrié, V Coronas, B Constantin - Cell Calcium, 2019 - Elsevier
Cancer stem cells are a subpopulation of tumor cells that proliferate, self-renew and produce
more differentiated tumoral cells building-up the tumor. Responsible for the sustained …

[HTML][HTML] The calcium channel α2δ1 subunit: Interactional targets in primary sensory neurons and role in neuropathic pain

W Cui, H Wu, X Yu, T Song, X Xu, F Xu - Frontiers in Cellular …, 2021 - frontiersin.org
Neuropathic pain is mainly triggered after nerve injury and associated with plasticity of the
nociceptive pathway in primary sensory neurons. Currently, the treatment remains a …

[HTML][HTML] Emerging roles for multifunctional ion channel auxiliary subunits in cancer

AS Haworth, WJ Brackenbury - Cell Calcium, 2019 - Elsevier
Several superfamilies of plasma membrane channels which regulate transmembrane ion
flux have also been shown to regulate a multitude of cellular processes, including …

Calcium channel subunit α2δ-1 as a potential biomarker reflecting illness severity and neuroinflammation in patients with acute ischemic stroke

X Xiong, L Zhang, Y Li, S Guo, W Chen, L Huang… - Journal of Stroke and …, 2021 - Elsevier
Background Voltage-gated calcium channels (VGCCs) dysfunction is involved in the
development of acute ischemic stroke (AIS). As a subunit of VGCC complexes, we detected …

Ca2+ Transportome and the Interorganelle Communication in Hepatocellular Carcinoma

HT Lai, RJ Canoy, M Campanella, Y Vassetzky… - Cells, 2022 - mdpi.com
Hepatocellular carcinoma (HCC) is a type of liver cancer with a poor prognosis for survival
given the complications it bears on the patient. Though damages to the liver are …

Targeting Ca2+ Signaling in the Initiation, Promotion and Progression of Hepatocellular Carcinoma

ES Ali, GY Rychkov, GJ Barritt - Cancers, 2020 - mdpi.com
Simple Summary Liver cancer (hepatocellular carcinoma) is a significant health burden
worldwide. It is often not detected until at an advanced stage when there are few treatment …

Increased serum calcium level promotes the risk of lymph node metastasis in endometrial cancer

XC Li, YY Dong, Y Cheng, JY Zhou… - Cancer Management …, 2020 - Taylor & Francis
Purpose The early predictive values of diagnostic markers for lymph node metastasis (LNM)
in endometrial cancer (EC) are still unclear at present. The purpose of this study is to explore …

Role of the Ca2+ channel α2δ-1 auxiliary subunit in proliferation and migration of human glioblastoma cells

M Fernández-Gallardo, A Corzo-Lopez… - Plos one, 2022 - journals.plos.org
The overexpression of α2δ-1 is related to the development and degree of malignancy of
diverse types of cancer. This protein is an auxiliary subunit of voltage-gated Ca2+ (CaV) …

[HTML][HTML] Biomarkers vs imaging in the early detection of hepatocellular carcinoma and prognosis

LA Balaceanu - World Journal of Clinical Cases, 2019 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the 5 th most frequently diagnosed cancer in the world,
according to the World Health Organization. The incidence of HCC is between 3/100000 …